Full Description
This authoritative and comprehensive 1996 publication looks in depth at a range of medical syndromes characterised by serious and unpredicted internal overheating of the body. These episodes may arise suddenly and unexpectedly in certain individuals, with life-threatening consequences, either as a result of heat stress, exceptional physical exertion or in response to certain common anaesthetics and some drugs, including ecstasy. The chapters focus on the full range of these syndromes, their metabolic and physiological basis, the important pre-disposing factors for the prediction of those at risk, and the medical management of these conditions. The volume includes important contributions from authors of international repute and incorporates a wealth of information from the Leeds malignant hyperthermia investigation unit. This compilation will be of interest to those wanting to understand these disorders.
Contents
Part I. Exertional Heatstroke: 1. History and epidemiology: definitions and groups at risk J. G. Dickinson; 2. Predisposing factors, clinical features, treatment and prevention J. G. Dickinson; 3. Pathophysiology of heatstroke J. P. Knochel; 4. Investigation of heat stroke victims 1: the human physiology laboratory C. G. Batty and W. A. Freeland; 5. Investigation of heat stroke victims 2: nuclear magnetic resonance spectroscopy J.-F. Payen and P. Stieglitz; 6. Investigation of exertional heat stroke 3: in vitro skeletal muscle contracture testing P. M. Hopkins, P. J. Halsall and F. R. Ellis; 7. Future research in exertional heat stroke P. M. Hopkins; Part II. Malignant Hyperthermia: 8. The clinical presentation of malignant hyperthermia P. J. Halsall; 9. Malignant hyperthermia: clinical management G. A. Gronert and J. F. Antognini; 10. Pathophysiology of malignant hyperthermia J. E. Fletcher and H. Rosenberg; 11. Screening for malignant hyperthermia susceptibility P. J. Halsall; 12. Skeletal muscle morphology P. Harnden; 13. The genetics of malignant hyperthermia Sarah P. West; 14. Porcine stress syndrome J. Dinsmore and G. M. Hall; Part III. Other Hypermetabolic Syndromes: 15. Neuroleptic malignant syndrome P. J. Adnet, H. Reyford and R. M. Krivosic-Horger; 16. Hyperthermic and hypermetabolic disorders J. A. Henry; 17. Hypermetabolism in endocrine disorders P. Belchetz; Index.
