基本説明
Foreword by Joseph T. Coyle.
Full Description
This 2000 publication reviews the rapid development of functional neuroimaging techniques and their implications for child psychiatry. It is unusual in its focus on children, and in integrating brain mapping with genetics and behavioural testing. This reference will help clinicians and investigators to: • Understand through imaging the mechanisms of childhood psychiatric disorders • Decide which technique is most appropriate for their purposes, with respect to technology, experimental design, data analysis and ethical considerations • Appreciate the role of molecular genetics and neuropsychology in planning brain imaging studies Coverage includes description of brain imaging strategies and the application to children of imaging techniques used in adults, set against an overview of normal behavioural and cognitive development. Linking the latest findings from neuroimaging to neurophysiological models, this is an essential resource for researchers and clinicians concerned with neurodevelopmental disorders.
Contents
Foreword Joseph Coyle; Preface Monique Ernst and Judith Rumsey; Part I. Techniques of Functional Neuroimaging: 1. Functional brain imaging with PET and SPECT Peter Herscovitch and Monique Ernst; 2. Modeling of PET/SPECT receptor images Evan Morris, Raymond Muzic, Bradley Christian, Christopher Endres and Ronald Fisher; 3. Techniques of functional neuroimaging: functional magnetic resonance imaging (fMRI) Guinevere F. Eden and Thomas A. Zeffiro; 4. MRS in childhood psychiatric disorders Deborah Yurgelun-Todd and Perry Renshaw; 5. Magnetoencephalography (MEG) Donald Rojas, Peter Teale and Martin Reite; Part II. Ethical Issues in Neuroimaging Reseach with Children Eugene Arnold, Alan Zametkin, Lauren Caravella and Nicole Korbly; Part III. Normal Development: 6. Brain development and evolution Manuel Casanova, Daniel Buxhoeveden and Gurkirpal Sohal; 7. Cognitive development from a neuropsychological perspective Daisy Pascualvaca and Gloria Morote; 8. Cognitive and behavioural probes of developmental landmarks for use in functional neuroimaging B. J. Casey, Kathleen Thomas, Tomihisa Welsh, Rona Livnat and Clayton Eccard; Part IV. Psychiatric Disorders: 9. Autism Diane Chugani; 10. Functional imaging in childhood onset schizophrenia Leslie Jacobsen and Alessandro Bertolino; 11. Pediatric mood disorders and neuroimaging Robert A. Kowatch, Pablo Davanzo and Graham J. Emslie; 12. New frontiers in neuroimaging of childhood onset anxiety disorders David Rosenberg, Lori Paulson, Frank MacMaster and Gregory Moore; 13. Functional brain imaging in Tourette's syndrome: what are we really imaging? Bradley Peterson and Prakash Thomas; 14. Functional neuroimaging in dyslexia: conceptual issues and psychiatric comorbidity Frank Wood and Lynn Flowers; 15. Attention deficit hyperactivity disorder: neuroimaging and behavioural/cognitive probes Julie B. Schweitzer, Carl Anderson and Monique Ernst; 16. Eating disorders Uttom Chowdhury, Isky Gordon and Bryan Lask; Part V. Future Directions: 17. Techniques of molecular genetics David Vandenbergh; 18. Issues in the genetic study of complex neurobehavioral conditions David Pauls; 19. The duplicity of plasticity: a conceptual approach to the study of early lesions and developmental disorders Ralph Axel Mueller and Eric Courchesne; 20. Utility of the CANTAB battery in functional neuroimaging A. C. H. Lee, A. M. Owen, R. D. Rogers, B. J. Sahakian and T. W. Robbins; 21. Neurodevelopmental assessment of cognitive function using the Cambridge Neuropsychological Testing Automated Battery (CANTAB): validation and future goals Monica Luciana and Charles Nelson; 22. Functional neuroimaging in child psychiatry: future directions Monique Ernst and Judith Rumsey; Glossary; Index.
