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Full Description
One of a five-volume collection that deals with different areas of interest concerning parallel aspects of environmental mutagenesis. This volume focuses on the basic science of environmental mutagenesis.
Contents
Partial table of contents:; PLENARY LECTURES; Basic Mechanisms and Environmental Mutagenesis--A Look Ahead (B. Bridges); BROAD MUTATIONAL MECHANISMS; Evolutionary Significance of Genetic Stability and Change (R. Haynes); ADDUCTION AND DNA DAMAGE; The Role of Carcinogen DNA Adduct Structure in the Induction of Mutations (E. Loechler, et al.); RECOMBINATION AND GENE CONVERSION; Transposable Genetic Elements: Agents of Complex Change (D. Galas); REPAIR: PROKARYOTE MECHANISMS AND INDUCTION; Oxidative DNA Damage: Repair and Inducible Cellular Responses (B. Demple); REPAIR: LOWER EUKARYOTE AND PLANT MECHANISMS; DNA Repair in Higher Plants (J. Veleminsky & K. Angelis); REPAIR: HIGHER EUKARYOTE MECHANISMS AND SELECTIVITY; The Role of the Nuclear Matrix in DNA Repair (L. Mullenders, et al.); REPAIR: HUMAN GENES AND MECHANISMS; How Cells Recognize Damaged DNA: Clues from Xeroderma Pigmentosum and Yeast (G. Chu, et al.); MUTATION: SPECTRA AND MECHANISMS; DNA-Damage-Inducible Genes in Mammalian Cells (A. Fornace, et al.); MUTATION: SHUTTLE VECTORS; Analysis of Spontaneous and UV-Induced Mutagenesis on SV40: Pyrimidine Dimers Versus Pyrimidine (6-4) Pyrimidones and Viral Infection Versus DNA Transfection (F. Bourre, et al.); MUTATION: TRANSGENIC ANIMALS; Transgenic Mice as a Model to Study Gene Mutations: Application as a Short-Term Mutagenicity Assay (J. Gossen & J. Vijg); NEW METHODS: POLYMERASE CHAIN REACTION; Screening for Base Mutations in the PAH and HPRT Loci Using the Polymerase Chain Reaction (PCR) in Combination with Denaturing Gradient Gel Electrophoresis (DGGE) (A-L Bxrresen, et al.); Index.
