Full Description
This is "Volume 2Medicinal Chemistry and Drug Discovery, 6th Edition". This new volume contains critical new chapters on Combinational Chemistry and Multiple Parallel Synthesis, High Throughput Pharmacology, and Retrometabolism Based Drug Design and Targeting.
Contents
Combinatorial Chemistry and Multiple Parallel Synthesis (L. Mitscher & A. Dutta).Highthroughput Screening for Lead Discovery (J. Houston & M. Banks).High-Throughput Pharmacology (S. Brown, et al).The Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery (S. Basu).Oligonucleotide Therapeutics (S. Crooke).Therapeutic Agents Acting on RNA Targets (J. Rife).Carbohydrate-Based Therapeutics (J. Musser).Membrane Transport Proteins and Drug Transport (P. Swaan).Allosteric Proteins and Drug Discovery (J. Bell).Receptor Targets in Drug Discovery and Development (M. Williams).Nicotinic Acetylcholine Receptors (D. Colquhoun, et al).Large-Scale Synthesis (F. Gupton).Principles of Drug Metabolism (B. Testa & W. Soine).Metabolic Considerations in Prodrug Design (L. Balant).Retrometabolism-Based Drug Design and Targeting (N. Bodor & P. Buchwald).Drug Discovery: The Role of Toxicology (J. Moe & J. McKim).Drug Absorption, Distribution, and Elimination (L. Benet, et al).Physicochemical Characterization and Principles of Oral Dosage Form Selection (G. Amidon , et al).The FDA and Regulatory Issues (W. Rzeszotarski).Intellectual Property in Drug Discovery and Biotechnology (R. Kaba, et al).Index.



