Full Description
Exposure to a wide variety of chemicals and drugs has become common in industrial, laboratory, and even household environments. Fortunately, global understanding and consequently global safety standards regarding the management of toxic and hazardous substances are fast approaching uniformity. The methods of handling, use, transportation, storage, and disposal in particular are moving toward standardization. As these protocols involving chemicals and drugs continue to cross international borders, students and professionals need a reliable resource to ensure they observe appropriate safety standards. The Industrial Guide to Chemical and Drug Safety covers not only current standards, but also a wealth of information on toxins to help regulatory bodies develop new protocols.
Written in an accessible narrative style, the Guide covers chemicals by key classes such as solvents, pesticides, and metals, and also by key industries such as drugs, food additives, plastics, cosmetics, detergents, and soaps. The book explains the beneficial and harmful aspects of a broad range of materials to which students, trainees, skilled workers, managers, and personnel associated with regulatory agencies are exposed, with the purpose of helping them avoid the illnesses associated with the misuse of chemicals and drugs. Chapters include:
-Heavy Metals
-Pesticides
-Industrial Solvents
-Industrial Gases and Fumes
-Drugs
-Target Organ Toxicity
-Disposal of Hazardous Chemicals
-Guidance to Students and Workers
-Good Laboratory Practice
Contents
Foreword xxiii
Preface xxv
Acknowledgments xxvii
Chapter 1 Introduction to Chemical and Drug Safety 1
Chapter 2 Principles of Toxicity and Safety 19
Chapter 3 Heavy Metals 59
Chapter 4 Organochlorine Pesticides 89
Chapter 5 Organophosphorus Pesticides 123
Chapter 6 Herbicides and Fungicides 157
Chapter 7 Carbamates 184
Chapter 8 Synthetic Pyrethroids, Fumigants, and Rodenticides 198
Chapter 9 Industrial Solvents 207
Chapter 10 Food Additives and Food Contaminants 242
Chapter 11 Industrial Gases and Fumes 252
Chapter 12 Drugs: Discovery and Development 259
Chapter 13 Drugs and Human Diseases 275
Chapter 14 Nonmedical Use of Drugs 320
Chapter 15 Drugs and Pharmaceuticals: Safety Considerations 332
Chapter 16 Target Organ Toxicity 377
Chapter 17 Disposal of Hazardous Chemicals 408
Chapter 18 Good Laboratory Practice 429
Chapter 19 Safety Evaluation: Methods and Procedures 465
Chapter 20 Guidance for Laboratory Students and Occupational Workers 504
Appendixes 521
Glossary 597
Index 617
