イオンチャネルと受容体のコレステロール調節<br>Cholesterol Regulation of Ion Channels and Receptors

個数:
電子版価格 ¥12,888
  • 電書あり
  • ポイントキャンペーン

イオンチャネルと受容体のコレステロール調節
Cholesterol Regulation of Ion Channels and Receptors

  • 在庫がございません。海外の書籍取次会社を通じて出版社等からお取り寄せいたします。
    通常6~9週間ほどで発送の見込みですが、商品によってはさらに時間がかかることもございます。
    重要ご説明事項
    1. 納期遅延や、ご入手不能となる場合がございます。
    2. 複数冊ご注文の場合、分割発送となる場合がございます。
    3. 美品のご指定は承りかねます。
  • ≪洋書のご注文につきまして≫ 「海外取次在庫あり」および「国内仕入れ先からお取り寄せいたします」表示の商品でも、納期の目安期間内にお届けできないことがございます。あらかじめご了承ください。

  • 製本 Hardcover:ハードカバー版/ページ数 289 p.
  • 言語 ENG
  • 商品コード 9780470874325
  • DDC分類 612.12

Full Description


This book brings together the most up-to-date knowledge about the role of cholesterol in regulation of ion channels and receptors and the pathological implications of these effects. It provides a comprehensive critical overview of the field comprised of three sections focusing on the impact of cholesterol on membrane structure, cholesterol regulation of ion channels and cholesterol regulation of receptors. This resource stands as a primary source of information for researchers both in academia and industrial drug development alike.

Table of Contents

Foreword                                           vii
Preface ix
Contributors xi
I CHOLESTEROL REGULATION OF MEMBRANE 1 (44)
PROPERTIES
1 Cholesterol Trafficking And Distribution 3 (24)
Between Cellular Membranes
Daniel Wustner
Lukasz Michael Solanko
Frederik W. Lund
2 Cholesterol Regulation Of Membrane 27 (18)
Protein Function By Changes In Bilayer
Physical Properties - An Energetic
Perspective
Jens A. Lundbaek
Olaf S. Andersen
II Cholesterol Regulation Of Ion Channels 45 (136)
3 Insights Into Structural Determinants Of 47 (22)
Cholesterol Sensitivity Of Kir Channels
Avia Rosenhouse-Dantsker
Irena Levitan
4 Role Of Lipid Rafts In The Regulation Of 69 (22)
Store-operated CA2+ Channels
Hwei L. Ong
Indu S. Ambudkar
5 Cholesterol Regulation Of Cardiac Ion 91 (18)
Channels
Elise Balse
Stephane Hatem
Stanley Nattel
6 Differential Contribution Of BK Subunits 109(26)
To Nongenomic Regulation Of Channel
Function By Steroids
Alex M. Dopico
Anna N. Bukiya
Aditya K. Singh
7 Regulation Of K+ Channels By 135(26)
Cholesterol-rich Membrane Domains In The
Immune System
Nuria Comes
Antonio Felipe
8 Indirect Channel Regulation By 161(20)
Cholesterol: The Role Of Caveolae And
Caveolins In Regulating KATP Channel
Function
Caroline Dart
III Cholesterol Regulation Of Receptors 181(100)
9 Regulation Of The Nicotinic Acetylcholine 183(22)
Receptor By Cholesterol As A Boundary Lipid
Francisco J. Barrantes
10 Specific And Nonspecific Regulation Of 205(26)
GPCR Function By Cholesterol
Gerald Gimpl
Katja Gehrig-burger
11 Structural Insights Into Cholesterol 231(24)
Interactions With G-Protein-Coupled
Receptors
Jeremiah S. Joseph
Enrique E. Abola
Vadim Cherezov
12 Membrane Cholesterol: Implications In 255(18)
Receptor Function
Sandeep Shrivastava
Amitabha Chattopadhyay
13 The Role Of Cholesterol And Lipid Rafts 273(8)
In Regulation Of TLR Receptors
Ruxana T. Sadikot
Index 281