Full Description
Metabolism includes various pathways of chemical reactions; understanding these pathways leads to an improved knowledge of the causes, preventions, and cures for human diseases. Medical Biochemistry: Human Metabolism in Health and Disease provides a concise yet thorough explanation of human metabolism and its role in health and diseases. Focusing on the physiological context of human metabolism without extensive consideration of the mechanistic principles of underlying enzymology, the books serves as both a primary text and resource for students and professional in medical, dental, and allied health programs.
Contents
Preface vi
Acknowledgments ix
The Authors xi
1 Introduction to Metabolism 1
2 Enzymes 11
3 Digestion and Absorption 38
4 Glycolysis 58
5 Pyruvate Dehydrogenase and the Tricarboxylic Acid Cycle 77
6 Electron Transport and Oxidative Phosphorylation 89
7 The Pentose Phosphate Pathway 102
8 Glycogen 112
9 Gluconeogenesis 126
10 Fatty Acid Oxidation and Ketones 141
11 Fatty Acid Synthesis 162
12 Triacylglycerol Transport and Metabolism 177
13 Ethanol 191
14 Phospholipids and Sphingolipids 199
15 Eicosanoids 218
16 Glycolipids and Glycoproteins 231
17 Cholesterol Synthesis and Transport 246
18 Steroids and Bile Acids 271
19 Nitrogen Homeostasis 290
20 Amino Acids 305
21 Sulfur Amino Acid Metabolism 325
22 Folate and Vitamin B12 in One-carbon Metabolism 335
23 Purines and Pyrimidines 351
24 Heme and Iron 372
25 Integration of Metabolism 393
Index 411
