基本説明
免疫学の主要ポイントを押えたコンパクトな人気教科書。
5TH: 2003.
Full Description
Immunologytopics of modern immunology in clear and succinct yet comprehensive fashion. The authors offer a uniquely balanced coverage of classical and contemporary approaches, basic and clinical aspects. As with the previous editions, the strength of the text is in a complete review of modern immunology without burdening the reader with excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics illustrated by uniformly drawn, full-color illustrations, many brand new to this edition. The sixth edition of this successful textbook newly covers: Toll-like receptors, their ligands and intracellular activation pathways The key role of activation induced cytidine deaminase (AID) in somatic hypermutation and class switch recombination. The autoimmune regulator ( AIRE) gene in self-tolerance and autoimmunity T and B cell activation and the immunological synapse, as well as characterization and mechanisms of action of T regulatory cells Praise for the previous edition: "This book is clearly a precious resource for undergraduate, graduate and medical students alike...For those who need an introduction to the fascinating world of immunology, this book should most certainly spark the interest." ANNALS OF BIOMEDICAL ENGINEERING "...an excellent beginner's guide...the authors have done a terrific job of providing an overview of the field." YALE JOURNAL OF BIOLOGY AND MEDICINE
Contents
About the Authors, xvii Contributors, xviii Preface and Acknowledgments, xix 1 OVERVIEW OF THE IMMUNE SYSTEM, 1 2 ELEMENTS OF INNATE AND ACQUIRED IMMUNITY, 11 3 IMMUNOGENS AND ANTIGENS, 29 4 ANTIBODY STRUCTURE AND FUNCTION, 41 5 ANTIGEN-ANTIBODY INTERACTIONS, IMMUNE ASSAYS, AND EXPERIMENTAL SYSTEMS, 61 6 THE GENETIC BASIS OF ANTIBODY STRUCTURE, 81 7 BIOLOGY OF THE B LYMPHOCYTE, 93 8 ROLE OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN THE IMMUNE RESPONSE, 107 9 BIOLOGY OF THE T LYMPHOCYTE, 125 10 ACTIVATION AND FUNCTION OF T AND B CELLS, 141 11 CYTOKINES, 165 12 TOLERANCE AND AUTOIMMUNITY, 183 13 COMPLEMENT, 205 14 HYPERSENSITIVITY: TYPE I, 221 15 HYPERSENSITIVITY: TYPES II AND III, 237 16 HYPERSENSITIVITY: TYPE IV, 247 17 IMMUNODEFICIENCY DISORDERS AND NEOPLASIAS OF THE LYMPHOID SYSTEM, 255 18 TRANSPLANTATION, 285 19 TUMOR IMMUNOLOGY, 299 20 RESISTANCE AND IMMUNIZATION TO INFECTIOUS DISEASES, 313 Glossary, 337 Appendix: Partial List of CD Antigens, 365 Index, 369
