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基本説明
Describes the development of a successful laser-based technique to improve the
bio-compatibility of selected ceramics and metals used for bone implants by the way of modifying their wettability characteristics.
Full Description
The biomaterials technology industry is already well established in the western world and is growing rapidly within Asian Pacific nations. It is often described as the 'next electronics industry', whilst the laser is described as a 'solution looking for a problem'. This book describes the use of the laser to solve a troublesome and costly problem in a rapidly growing global industry. The authors have spent many years conducting research using laser materials processing and wettability characteristics and have perfected a technique to improve the bio-compatibility of various bone-implant materials using laser irradiation. They have made pioneering discoveries on the subject and established some generic theories and principals that will have a wide range of applications in the biomaterials field.
Introduces inter-disciplinary research work covering laser materials processing and surface modification of biomaterials for enhanced compatibility.
Includes highly scientific and novel research material.
Serves both as a practitioner guide and a reference book.
Covers an exciting and rapidly developing area of technology that is of keen interest to engineers and clinicians alike.
Laser Surface Treatment of Bio-Implant Materials is rare in providing a reference source that describes specifically a mechanical engineering solution to a biotechnology problem. It serves as both a practitioner guide and a medium to high-level reference text book, and as such is a reference source for the engineer practising or looking to move into the biomaterials field, undergraduate and post graduate students and those conducting bio-related research in either academia or industry. It will prove useful to mechanical engineers, biotechnologists, biomechanical engineers, metallurgists, clinicians and even surgeons.
Contents
Acknowledgements. Introduction.
1. Bioactivity and Biointegration of Orthopaedic and Dental Implants.
1.1. Introduction.
1.3. Biointegration of Orthopaedic and Dental Implants.
1.4. Controlling the Bone-Implant Interface.
2. Surface Modification of Biomaterials.
2.1. Introduction.
2.3. Metallic Implants.
2.4. Surface Modification of Biomaterials.
2.5. Laser Surface Modification of Biomaterials.
3. Wettability in Biomaterials Science and Modification Techniques.
3.1. Introduction.
3.2. Wettability, Adhesion and Bonding Theoretical Background.
3.3. Wettability in Biomaterial Science.
3.4. Current Methods of Wettability Modification.
3.5. Laser Wettability Characteristics Modification.
4. CO2 Laser Modification of the Wettability Characteristics of Magnesia Partially Stabilised Zirconia.
4.1. Introduction.
4.2. Experimental Procedures.
4.3. The Effects of CO2 Laser Radiation on Wettability Characteristics.
4.4. Surface Energy and its Component Parts.
4.5. Identification of the Predominant Mechanisms Active in Determining Wettability Characteristics.
4.6. The Role Played by Microstructures in Terms of Crystal Size and Phase in Effecting Surface Energy Changes.
4.7. Investigation of Wettability and Work Adhesion Using Physiological Liquids.
4.8. Summary.
5. In vitro Biocompatibility Evaluation of CO2 Laser Treated Magnesia Partially Stabilised Zirconia.
5.1. Introduction.
5.2. Sample Preparation.
5.3. Bone Like Apatite Formation.
5.4. Protein Adsorption.
5.5. Osteoblast Cell Response.
5.6. Predictions for Implantation in an in vivo Clinical Situation.
5.7. Summary.
6. The Effects of CO2 Laser Radiation on the Wettability Characteristics of a Titanium Alloy.
6.1. Introduction.
6.2. Experimental Procedures.
6.3. The Effects of CO2 Laser Radiation on Wettability Characteristics.
6.4. Surface Energy and its Component Analysis.
6.5. Identification of the Predominant Mechanisms Active in Determining Wettability Characteristics.
6.6. Investigation of Wettability and Work Adhesion Using Physiological Liquids.
6.7. Summary.
7. In vitro Biocompatibility Evaluation of CO2 Laser Treated Titanium Alloy.
7.1. Introduction.
7.2. Sample Preparation.
7.3. Bone Like Apatite Formation on Titanium Alloys.
7.4. Protein Adsorption.
7.5. Osteoblast Cell Adhesion.
7.6. Predictions for Implantation in an in vivo Clinical Situation.
7.7. Summary.
8. Enquiry into the Possible Generic Effects of the CO2 Laser Treatment on Bone Implant Biomaterials.
8.1. Introduction.
8.2. Ascertaining the Generic Effects of CO2 Laser Treatment on Bioinert Ceramics.
8.3. Ascertaining the Generic Effects of CO2 Laser Treatment on Metal Implants.
8.4. Summary.
Conclusions.
References.
Index.
