Full Description
Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value.
The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases.
Contents
FOREWORD: THE CONCEPT OF IMMUNODIAGNOSIS
INTRODUCTION: AUTOANTIBODIES-UNIQUE CHARACTERISTICS
ALLERGIC DISEASE AUTOANTIBODIES
ANTINEUTROPHIL ANTIBODIES
INTRODUCTION: ANTINUCLEAR ANTIBODIES
AUTOANTIBODIES TO BIOLOGIC FACTORS/STRUCTURES
CARDIAC AUTOANTIBODIES
ENDOCRINE AUTOANTIBODIES
GI AND LIVER AUTOANTIBODIES
HEMATOLOGIC AUTOANTIBODIES
KIDNEY AUTOANTIBODIES
NEUROLOGICAL SYSTEM AUTOANTIBODIES
RHEUMATIC DISEASE AUTOANTIBODIES
SKIN DISEASE AUTOANTIBODIES
UNIQUE CLINICAL SITUATIONS
