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基本説明
New revised edition of this bestseller, which teaches the importance of metals in biology, the environment and medicine. 1st ed.: 2007.
Full Description
Biological Inorganic Chemistryand Function, Second Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. Beginning with an overview of metals and selected nonmetals in biology, the book then discusses the following concepts: basic coordination chemistry for biologists; structural and molecular biology for chemists; biological ligands for metal ions; intermediary metabolism and bioenergetics; and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment.
Contents
1. An Overview of Metals and Selected Nonmetals in Biology 2. Basic Coordination Chemistry for Biologists 3. Structural and Molecular Biology for Chemists 4. Biological Ligands for Metal Ions 5. An Overview of Intermediary Metabolism and Bioenergetics 6. Methods to Study Metals in Biological Systems 7. Metal Assimilation Pathways 8. Transport, Storage, and Homeostasis of Metal Ions 9. Sodium and Potassium - Channels and Pumps 10. Magnesium-Phosphate Metabolism and Photoreceptors 11. Calcium - Cellular Signalling 12. Zinc - Lewis Acid and Gene Regulator 13. Iron 14. Copper - Coping with Dioxygen 15. Nickel and Cobalt 16. Manganese - Oxygen Generation and Detoxification 17. Molybdenum, Tungsten, Vanadium, and Chromium 18. Non-metals in Biology 19. Biomineralisation 20. Metals in Brain 21. Metals and Neurodegeneration 22. Metals in Medicine and Metals as Drugs 23. Metals in the Environment