Deciphering Cancer Resistance : Mechanisms, Targets, and Emerging Therapies (Novel approaches to overcome cancer resistance to conventional therapies)

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Deciphering Cancer Resistance : Mechanisms, Targets, and Emerging Therapies (Novel approaches to overcome cancer resistance to conventional therapies)

Pedroza, Abraham (EDT)/ Alvarez-Gomez, Rosa M. (EDT)

ウェブストア価格 ¥38,684（本体¥35,168）
Academic Press Inc（2026/08発売）
外貨定価 US$ 175.00
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ポイント 1,755pt

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製本 Paperback:紙装版/ペーパーバック版／ページ数 330 p.
言語 ENG
商品コード 9780443456596

Full Description

Deciphering Cancer Resistance: Mechanisms, Targets, and Emerging Therapies addresses the critical challenge of treatment resistance in oncology. The book provides a comprehensive examination of the cellular, molecular, and genetic mechanisms behind resistance, unveiling insights from cancer biology and genomics that inform novel therapeutic strategies. Sections explore cutting-edge technologies like CAR-T cell therapy, nanotechnology, and artificial intelligence, highlighting their role in discovering new treatment modalities. Readers will find the latest preclinical and clinical data, including newly FDA-approved therapies, demonstrating their potential to improve patient outcomes.

For academics, this resource consolidates the latest research and clinical developments, aiding researchers, clinicians, and students in staying updated on advancements. It will also be a great guide for graduate studies and research, offering critical insights into drug development and targeted therapies for professionals in the pharmaceutical and biotechnology sectors, ultimately driving progress in cancer treatment.

Part I: Molecular and Cellular Mechanisms Underlying Cancer Resistance (Chapters 1-5)
1. Molecular Pathways in Cancer Resistance: A Comprehensive Overview
2. Role of Tumor Microenvironment in Therapy Resistance
3. Epigenetic Modifications and Drug Resistance in Cancer
4. Cancer Stem Cells as Drivers of Resistance to Conventional Therapies
5. Mechanisms of Immune Escape and Resistance to Immunotherapy in Cancer Treatment

Part II: Emerging Therapeutic Approaches to Overcome Resistance (Chapters 6-13)
6. Targeting Epigenetic Regulators: Promising Avenues
7. CRISPR and Gene Editing in Combating Drug Resistance
8. Synthetic Lethality and PARP Inhibitors in Resistant Tumors
9. Role of Nanomedicine in Delivering Targeted Therapies
10. Overcoming Resistance to Immunotherapy with Checkpoint Blockade
11. Exploiting Tumor Metabolism to Reverse Resistance
12. The Role of MicroRNAs and Non-coding RNAs in Therapeutic Resistance
13. Overcoming Cancer Resistance: The Role of Emerging CAR-T Cell Approaches

Part III: Clinical Applications and Future Perspectives (Chapters 14-18)
14. Biomarker Development for Predicting Therapy Resistance
15. Precision Medicine in the Context of Cancer Resistance
16. Combination Therapies to Enhance Treatment Efficacy in Resistant Cancers
17. AI-Driven Approaches to Overcoming Cancer Resistance
18. Future Directions in Overcoming Cancer Resistance: Challenges and Opportunities