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Full Description
Cyclic Peptides, Volume 721 covers peptide structures and their enhancement, stability, specificity, and overall functionality. As a growing suite of computational and experimental tools support the discovery and optimization of these molecules, ranging from well-established modeling platforms to emerging deep-learning algorithms that expand design possibilities, this book aims to provide a comprehensive overview of cyclic peptide research, covering fundamental principles, production strategies, and the latest technological advances in both synthetic and computational realms.
Cyclic peptides are a powerful approach to constraining peptide structures, enhancing their stability, specificity, and overall functionality. They can be generated through diverse techniques—including chemical synthesis, mRNA display, and DNA display—that enable the creation of tailored peptide libraries.
Contents
1. To be determined
Yu-Shan Lin
2. Using NMR Spectroscopy to Study the Folding and Supramolecular Assembly of Conformationally Constrained β-Sheet Peptides
James S. Nowick and Jason Zhu
3. To be determined
Ali Tavassoli
4. Using AEP enzymes to cyclize cyclotides: ultrastable constrained peptides
David J. Craik
5. Translational synthesis of constrained cyclic peptides using genetic code reprogramming"
Toby Passioura
6. To be determined
Parisa Hosseinzadeh and Paris Watson
7. To be determined
Parisa Hosseinzadeh, Noora Azadvari and Ben Burress-Irving
8. To be determined
Ben Brown
9. To be determined
Scott Lokey
10. Cyclic peptides as ligands for competition binding assays
James Inglese
11. To be determined
Alvaro Siano
12. To be determined
Gaurav Bhardwaj
13. To be determined
Vikram Khipple Mulligan
14. To be determined
Eugene Serebryany