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Full Description
Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
Contents
1. Extraction of Amyloids from Neurodegenerative Disease Tissues for Structural Analysis
Yang Yang, Mohammed Alhadidy, Tiara Hinton and Katelyn Ernst
2. Cryo-EM Structure Determination of Amyloid Fibrils: Methodology, Insights, and Practical Tools
Gunnar Schroder
3. Methods for studying molecular architecture of Ab aggregates in tissues using cryo-ET
Rene Werner Frank
4. Cryo-EM methods to study binding between amyloid fibrils and chemical compounds or ligan
Cong Liu, Dan Li, Qinyue Zhao and Kaien Liu
5. Dynamics studies of side-chains and hydration shells in amyloid-beta fibrils using deuterium and oxygen-17 solid-state NMR
Liliya Vugmeyster and Dmitry Ostrovsky
6. Technical aspects of pressure jump NMR applied to the study of Abeta and protein oligomerization
Adriaan Bax
7. Characterizations of the beta-amyloid-membrane interaction intermediates
Wei Qiang, Maurine Kengwerere and Tingyao Wang
8. Time-resolved solid-state NMR studies of oligomer formation.
Robert Tycko
9. Methods for characterizing the individual filament structures of amyloid peptide assemblies using atomic force microscopy
Wei-Feng Xue
10. Single-molecule fluorescence spectroscopy and imaging on heterogeneous amyloid beta aggregation
Hoi Sung Chung
11. Two-dimensional FT-IR methods on amyloid aggregation and folding pathways
Michal Maj
12. Application of EPR spectroscopy in the structural studies of Aβ oligomers and fibrils
Zhefeng Guo and Diana Portugal Barron
13. Identification of amyloid polymorphisms in brain tissues based on conformational-sensitive dyes
Carlo Condello
14. Molecular simulation methods for amyloid-membrane interactions
Birgit Strodel, Bastian Bundschuh and Franziska Kley
15. How to prepare Alzheimer's amyloid-beta oligomer samples with sufficient quantity and quality for solid-state NMR measurements
Anant K. Paravast
