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Full Description
This comprehensive volume explores the fundamental biological process of autophagy, a critical cellular mechanism responsible for the degradation and recycling of cellular components. Beginning with the historical discovery and molecular mechanisms of autophagy, the book delves into its regulation, physiological roles, and significance in maintaining cellular homeostasis. It highlights the diverse functions of autophagy in health, development, aging, and disease, including its involvement in cancer, neurodegeneration, infection, immunity, and metabolic disorders.
Contents
1. Ciliophagy: Maintaining Primary Cilium Homeostasis to Prevent Cilium-Related Diseases
Eugenia Morselli
2. Unraveling the interplay of glycolysis, lactylation, and autophagy
Marco Cordani
3. AUTOPHAGY AND TYPE 2 DIABETES: BRIDGING THE GAP IN METABOLIC HEALTH
David Muñoz Sebastián, Agustina Creus and Leonardo Ortega
4. Autophagy in Cancer Cachexia: From Mechanisms to Therapeutic Opportunities
Marc Beltrà, Riccardo Ballarò and Fabio Penna
5. Glycophagy: A Selective Autophagy Pathway for Glycogen Degradation
Pascual Sanz and Maria Adelaida Garcia-Gimeno
6. Role of Autophagy in Adipose Tissue: Implications for Metabolic Health
Montserrat Romero, Antonio Zorzano and Núria Borràs-Ferré



