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Full Description
Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health, while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease. The book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems. Written for a diverse audience including researchers, clinicians, students, and industry professionals, this book serves as an invaluable resource for understanding the critical roles of ApoE in health and disease. It provides a holistic view of current research, making it suitable for both experts in the field and those seeking an introduction to the topic. Through its comprehensive approach, the book aims to foster a deeper understanding of ApoE and inspire further research and clinical applications in this dynamic field.
Contents
1. Apolipoprotein E (ApoE): Structural Insights, Functionality, and Genetic Variability
2. Apolipoprotein E and Cardiovascular Pathophysiology: A Comprehensive Exploration
3. Apolipoprotein E in Alzheimer's Disease: Genetic Predisposition and Mechanistic Implications
4. Apolipoprotein E and Neurological Disorders: Beyond Alzheimer's Disease
5. Apolipoprotein E's Impact on Metabolic Syndrome: A Systematic Analysis
6. Apolipoprotein E and Liver Health: Implications in Lipid Metabolism and Disease
7. Apolipoprotein E and its Role in Cancer: Insights into Carcinogenic Associations
8. Apolipoprotein E's Immune Mediation: Implications in Inflammatory Disorders
9. Pharmacogenetics of Apolipoprotein E: Precision Medicine and Therapeutic Implications
10. Challenges and Prospects in Targeting ApoE for Disease Management
11. Apolipoprotein E and Infectious Diseases: A Framework for Therapeutic Developments
12. Genetic Engineering of Apolipoprotein E: Innovations and Clinical Applications
13. Apolipoprotein E and Precision Medicine: Individualized Disease Management Approaches
14. Apolipoprotein E in Drug Delivery Systems: Targeted Pharmacotherapeutics
15. Apolipoprotein E and Autoimmune Disorders: Therapeutic Frontiers
