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Full Description
Mitochondria and Cancer: From Basic Science to Clinical Applications - Understanding Pathogenesis, Therapy Resistance, and Disease Relapse is an essential reference for understanding the intricate relationship between mitochondria and cancer. The book explores cancer pathogenesis, therapy resistance, and disease relapse, all of which are significantly influenced by mitochondrial metabolism. Written for oncology researchers, it combines fundamental scientific knowledge with clinical relevance, providing recent findings and practical recommendations for cancer prevention and prognosis. This comprehensive guide covers the tumor microenvironment, cancer stem cells, microbiota, and resistance mechanisms while addressing novel topics like mitochondria-enhancing strategies and targeted therapies. With contributions from global experts, the book offers a well-rounded view of current research, making it a valuable resource for anyone in cancer biology or molecular biology fields.
Contents
1. Mitochondria: Origin, Structure, and Function
2. Mitochondrial Metabolism and Trafficking in Cancer
3. Mitochondrial Genome and Cancer
4. Mitochondrial-nuclear Crosstalk and Its Role in Cancer
5. Mitochondria and Tumor Microenvironment
6. Mitochondria and Cancer Stem Cells
7. Mitochondria, Exosome, Cancer
8. Mitochondria, Microbiota, Cancer
9. MiRNAs and Their Impacts on Cancer Cell's Mitochondria
10. Mitochondria and Cancer Prevention
11. Mitochondria and Cancer Diagnosis
12. Mitochondrial Metabolism as a Prognostic Biomarker (Mitochondria and Cancer Progression)
13. Mitochondria, Tumor Microenvironment, and Radioresistance
14. Mitochondria and Resistance to Chemotherapy
15. Mitochondria and Resistance to Targeted Therapies
16. Mitochondria and Resistance to Immunotherapy
17. Mitochondria Enhancing Strategies in Cancer
18. Advances in Targeted Anti-mitochondrial Therapies
19. Applying Magnetic Fields to Target Mitochondria
