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Full Description
The Gut Microbiome in Precision Medicine: From Research to Clinical Practice provides an in-depth look at the crucial influence of the gut microbiome on health and disease, focusing on gastrointestinal disorders like inflammatory bowel disease, irritable bowel syndrome, and colorectal cancer. The book outlines how advanced analysis of the gut microbiome is transforming approaches to personalized medicine, enabling tailored treatments and dietary recommendations in gastroenterology. It also discusses the practical challenges and opportunities of bringing microbiome analysis into clinical settings, particularly in developing countries, and begins with a comprehensive introduction to both the human microbiome and the concept of precision medicine.
Additionally, the book delves into multi-omics integration, covering genomics, transcriptomics, proteomics, and metabolomics techniques for profiling the gut microbiome. Readers will find detailed discussions of microbiome-based interventions, such as probiotics, prebiotics, and personalized nutrition strategies for managing gastrointestinal diseases. Real-world case studies and practical examples highlight how clinicians and healthcare practitioners can overcome barriers to implementing these analyses.
Contents
Section I: Introduction to the Microbiome and Precision Medicine
1. Definition and Importance of the Human Microbiome
2. Precision Medicine in Gastroenterology
3. Foundations of the Gut Microbiome
4. The Gut Microbiome: Composition, Diversity, and Influencing Factors
5. Epigenetic Influences of the Gut Microbiome
Section II: Multi-omics Integration: Unraveling the Complexities of the Gut Microbiome
6. Fundamentals of Multi-omics in Microbiome Research
7. Advanced Multi-omics Technologies in Gut Microbiome Research
8. Challenges in Integration of Multi-omics in Gut Microbiome
9. Comprehensive Analysis of the Gut Microbiome
10. Challenges and Limitations of Microbiome Analysis
11. Advanced Methods and Technological Advances in Personalized Microbiome Research
12. Precision Profiling for Tailored Health Solutions
13. Standardization and Quality Control in Microbiome Analysis
14. Microbiome Biomarkers and Multi-omics Approaches in Precision Medicine
15. Definition and Importance of the Microbiome Biomarkers
16. Overview of Microbiome Biomarkers and Their Applications in Gastroenterology
17. Personalized Gastroenterology: Inflammatory Bowel Disease
18. Role of the Gut Microbiome in the Pathogenesis of IBD
19. Microbiome-Based Biomarkers for IBD Diagnosis and Prognosis
20. Microbiome-Based Interventions for IBD Treatment
21. Personalized Gastroenterology: Irritable Bowel Syndrome
22. Role of the Gut Microbiome in the Pathogenesis of IBS
23. Microbiome-Based Biomarkers for IBS Diagnosis
24. Microbiome-Based Interventions for IBS Management
25. Personalized Gastroenterology: Colorectal Cancer
26. Role of the Gut Microbiome in the Development of Colorectal Cancer
27. Microbiome-Based Biomarkers for Colorectal Cancer Screening and Early Detection
28. Microbiome-Based Interventions for Colorectal Cancer Prevention and Treatment
Section III: Microbiome-Based Interventions: Probiotics and Prebiotics
29. Overview of Probiotics and Prebiotics
30. Mechanisms of Action of Probiotics and Prebiotics
31. Evidence for the Use of Probiotics and Prebiotics in Gastrointestinal Diseases
32. Personalized Nutrition and the Microbiome
33. Role of Diet in Shaping the Gut Microbiome
34. Personalized Nutrition Plans Based on Gut Microbiome Analysis
35. Examples of Successful Personalized Nutrition Interventions for Gastrointestinal Diseases
36. Implementing Microbiome Analysis in Clinical Practice
37. Challenges and Barriers to Implementing Microbiome Analysis in Clinical Practice
38. Implementing Microbiome Analysis in Clinical Practice: Overcoming Challenges
39. Case Studies of Successful Implementation of Microbiome Analysis in Clinical Practice
Section IV: Challenges and Opportunities of Personalized Gastroenterology in Developing Countries
40. Unique Challenges Faced by Developing Countries in Implementing Microbiome-Based Interventions
41. Personalized Medicine in Gastroenterology
42. Examples of Successful Microbiome-Based Interventions in Developing Countries
43. Barriers to Implementation in Precision Medicine
44. Bioethical Challenges in the Era of Precision Medicine
45. Artificial Intelligence in Precision Medicine: Enhancing Predictive Analytics
46. CRISPR and Genome Editing: Precision Tools for Personalized Therapies
Section V: Future Directions and Research Priorities in Gut Microbiome Personalized Medicine
47. Potential Applications of Microbiome Research in Other Areas of Gastroenterology
48. Collaboration and International Efforts to Advance the Field of Precision Gastroenterology
