Full Description
Theoretical and Clinical Geropharmacology, explores the emerging field of senotherapeutics, which focuses on targeting cellular senescence to reduce age-related diseases and promote healthy aging. Chapters in this new release include Senotherapeutics: Milestones, innovations, and future prospects, Game Changer: Navigating between challenges and hopes in Geropharmacology, Next-Gen Senotherapeutics: AI/ML-driven strategies for aging and age-related disorders, Pharmacological frontiers in senescence: Transforming senescence with drug repurposing, Pharmacological potential of calorie restriction mimetics in mitigating brain aging, Isothiocyanates from cruciferous plants as geroprotectors, and much more.
Other chapters cover Cellular parabiosis as a senotherapeutic approach, Molecular imaging for senescent cells-targeted therapeutics in aging and age-related diseases, Mitochondria-associated membranes (MAMs) in age-related heart diseases, role of endoplasmic reticulum stress, Cellular senescence and senotherapeutics in cardiovascular diseases, Risk of senescence, polypharmacy, and their outcomes in elderly cardiovascular disease patients, Geropharmacology and gastrointestinal surgery, Oxygen-ozone adjunct therapy in aging and senescence-related disorders, and more.
Contents
1. Senotherapeutics: Milestones, innovations, and future prospects
Ufuk Çakatay, Erdem Atasever and Mehmet Can Atayik
2. Game Changer: Navigating between challenges and hopes in Geropharmacology
Qian Chen, Lindon Young, Reid Hartman, Lidia Dankiv, Emily Yan and Robert Barsotti
3. Next-Gen Senotherapeutics: AI/ML-driven strategies for aging and age-related disorders
Kavitha Thirumurugan, Prashanth S. Javali, Subhajit Sarkar, Ashish Kumar, Sree Varshini R and Jose Mathew D
4. Pharmacological frontiers in senescence: Transforming senescence with drug repurposing :
Andleeb Shahzadi, Sibel Ozyazgan and Ufuk Çakatay
5. Pharmacological potential of calorie restriction mimetics in mitigating brain aging
Abhishek Kumar Singh
6. Isothiocyanates from cruciferous plants as geroprotectors
Volodymyr I. Lushchak
7. Cellular parabiosis as a senotherapeutic approach
Ilhan Onaran and Sevide Şencan
8. Molecular imaging for senescent cells-targeted therapeutics in aging and age-related diseases
Peili Cen
9. Mitochondria-associated membranes (MAMs) in age-related heart diseases, role of endoplasmic reticulum stress
Alejandro Silva-Palacios
10. Cellular senescence and senotherapeutics in cardiovascular diseases
Arttatrana Pal
11. Risk of senescence, polypharmacy, and their outcomes in elderly cardiovascular disease patients
Tamer Cebe and Fatih Kızılyel
12. Geropharmacology and gastrointestinal surgery
Anıl Orhan
13. Oxygen-ozone adjunct therapy in aging and senescence-related disorders. State of art
Salvatore Chirumbolo, Giovanni Ricevuti, Marianno Franzini and Francesco Vaiano
14. Polypharmacy-induced changes in the oral mucosa and jawbone in elderly
Mehmet Yaltırık, Kaan Erisildar and Sabahat Zeynep Yey Özkeskin
15. Senotherapeutic approach to age-related endocrine diseases
Gülnur Andican and Şeydanur Turgut
16. Polypharmacy as a reason for misinterpreting laboratory results in the elderly.
Ibrahim Murat Bolayırlı
