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Full Description
Advances in Microscale Electro- and Liquid Phase-Based Separation Techniques summarizes Microscale separation techniques characterized by fast, high resolution, and high efficiency with very reduced sample and solvent consumption. The book summarizes the existing body of knowledge, including hyphenated version to mass spectrometry (cLC-MS), capillary electrophoresis (CE), capillary zone electrophoresis (CZE and CZE-MS), micellar electrokinetic capillary chromatography (MEKC), capillary gel electrophoresis (CGE), capillary isoelectric focusing (CIEF), capillary isotachophoresis (CITP), capillary electrochromatography (CEC), microfluidics, and microchips. It then demonstrates the applicability of these techniques to existing and future problems in the analysis of complex mixtures of biochemicals, pharmaceuticals, environmental, and natural products.
This book will be valuable to separation scientists, applications scientists, and technicians in industrial outlets, including those in pharmaceuticals, biomedicals, biotechnologies, and food and environmental industries. Students and professors who study separation techniques will also benefit greatly from the book's content.
Contents
Part I: Capillary Electrophoresis (CE)
1. Fundamentals of capillary electrophoresis
2. Instrumentation of capillary electromigration methods, Optical Detection
3. Recent trends in C4D for capillary and microchip electrophoresis and its applications
4. Capillary gel electrophoresis
5. Capillary Zone Electrophoresis
6. Surfactants and other Additives for Micellar Electrokinetic Capillary Chromatography
7. Capillary Isoelectric Focusing: theory, instrumentation, applications, and limitations
8. Capillary Isotachophoresis
9. Capillary Electrophoresis-Mass Spectrometry
10. Noise reduction techniques for capillary electrophoresis and electrochromatography
11. Capillary electrophoresis in the control of residues and contaminants in food
12. Capillary electrophoresis in pharmaceutical analysis
13. Is capillary electrophoresis well adapted for lipid separations?
Part II: Capillary Electrochromatography (CEC)
14. Basic principles and operational aspects of capillary electrochromatography
15. Theory and practice of capillary electrochromatography-mass spectrometry: opportunities and challenges
16. Applications of capillary electrochromatography
Part III: Capillary Liquid Chromatography
17. Fundamentals of capillary liquid chromatography—basic principles, advantages and limitations
18. Instrumentation of capillary liquid chromatography
19. Capillary liquid chromatography-mass spectrometry: a case study on glycans and glycoconjugates
20. Applications of capillary liquid chromatography
Part IV: Microfluidics and Microchips-Based Techniques
21. Microchip capillary electrophoresis and capillary electrochromatography
22. Fabrication methods for microchip capillary electrophoresis and capillary electrochromatography and their coupling to mass spectrometry
23. Instrumentation for microfluidic capillary liquid chromatography
24. Nanoscale electrophoresis of biomolecules



