Reverse Aging : Current Research and Future Directions

個数：

予約

Reverse Aging : Current Research and Future Directions

Singh, Sandeep Kumar (EDT)/ Mishra, Shailendra Kumar (EDT)

ウェブストア価格 ¥36,467（本体¥33,152）
Academic Press Inc（2026/02発売）
外貨定価 US$ 175.00
ポイント 331pt

現在予約受付中です。出版後の入荷・発送となります。
（重要：表示されている発売日は予定となり、発売が延期、中止、生産限定品で商品確保ができないなどの理由により、ご注文をお取消しさせていただく場合がございます。予めご了承ください。）

●3Dセキュア導入とクレジットカードによるお支払いについて

【入荷遅延について】
世界情勢の影響により、海外からお取り寄せとなる洋書・洋古書の入荷が、表示している標準的な納期よりも遅延する場合がございます。
おそれいりますが、あらかじめご了承くださいますようお願い申し上げます。

◆画像の表紙や帯等は実物とは異なる場合があります。

◆ウェブストアでの洋書販売価格は、弊社店舗等での販売価格とは異なります。
また、洋書販売価格は、ご注文確定時点での日本円価格となります。
ご注文確定後に、同じ洋書の販売価格が変動しても、それは反映されません。

製本 Paperback:紙装版/ペーパーバック版／ページ数 350 p.
言語 ENG
商品コード 9780443331596

Full Description

Reverse Aging: Current Research and Future Directions explores the integrated approach of aging and reverse aging to present a comprehensive understanding of the biological, genetic, and molecular mechanisms associated with aging. By targeting fundamental aging mechanisms, strategies are being developed to reverse and repair damage and potentially lead to greater healthspan benefits and optimal longevity. The book opens with the fundamentals of aging and how genetic, environmental, and lifestyle variables affect the biological, psychological, and social processes that lead to aging before delving into a comprehensive review of the hallmarks of aging. Next, an overview of the concept of reverse aging is presented, and subsequent chapters examine specific reverse aging models and approaches. The book explores use of cellular reprogramming techniques, provides an overview of the molecular processes that underlie NANOG-mediated reversal aging, and discusses the possible contribution of IGF-1/PKA signaling reduction to reverse aging via HSC-based therapies. The developing science of rejuvenating stems cells, histone modification, and stimulation of autophagic activity to facilitate the removal of cellular debris and reduce the impact of aging on various organ systems as well as novel concepts of mRNA enhanced cell therapy, immunological-driven signaling, mitochondrial modulations, cell-cycle regulation, and metabolic reprogramming for reserve aging are all examined. The wide range of nutritional therapies, phytochemical, prescription medications, and nutraceuticals impacting the aging process is reviewed, and the book closes with discussion of the revolutionary role AI has on anti-aging research and where the field is headed. In conclusion, the book emphasizes the importance of targeting fundamental aging mechanisms to extend health and achieve optimal longevity and provides insights into the potential implications for healthcare and aging research, highlighting the need for collaborative efforts and interdisciplinary perspectives to address the challenges of population aging and develop effective strategies for healthy aging practices.

1. Aging: Concept, Theories, Principle and Future Prospective
2. Overview of Hallmark of Aging
3. Reverse Aging: Concept, Significance, Theories and Future Prospective
4. Reprogramming a Cell's Epigenetic Status for Reverse Aging
5. Cellular Reprogramming for Reverse Aging
6. NANOG: a Key Element for Reverse Aging
7. Reduction of IGF-1/PKA to Promote Hematopoietic-stem cell-based Reverse Aging
8. Rejuvenating Stem Cells to Reverse Aging
9. Histone Modification (H3K27) to Reverse Aging
10. Autophagy as a Therapeutic Target to Enhance Reverse Aging
11. mRNA Enhanced Cell Therapy and Reverse Aging
12. Reverse Aging Through Immune-driven Signaling
13. Mitochondrial Modulations for Reverse Aging
14. Reverse Aging by Regulating Cell-cycle
15. Metabolic Reprogramming for Reverse Aging
16. Diets, Phytochemicals, Drugs and Nutraceuticals for Reverse
17. Artificial Intelligence and Anti-aging Research