- ホーム
- > 洋書
- > 英文書
- > Science / Mathematics
Full Description
Alternative Splicing: Recent Advances in Health and Disease offers a comprehensive study of this cellular process, its fundamental characteristics, latest advances, and clinical utilization. Opening with an introduction to alternative splicing and its function in generating transcriptome and protein diversity, the book considers the role of this process across a range of diseases and disorders, including cardiovascular disease, cancer, obesity, and viral infections. Key methods used to study alternative splicing are also investigated, including high-throughput sequencing-based methods, bioinformatics tools, computational methods, single-cell sequencing techniques and mass-spectrometry based proteomics.
This is followed with analysis of therapeutic approaches associated with alternative splicing. This is an ideal reference for those involved in investigating alternative splicing and its impact to health and disease, and is therefore relevant to researchers across cell biology, molecular biology, pharmacology and related areas.
Contents
1. Alternative splicing: Introduction
2. Alternative splicing and cardiovascular diseases
3. Alternative splicing and cancer
4. Alternative splicing and obesity/diabetes
5. Alternative splicing and bacterial infections
6. Alternative splicing and fungal pathogenesis
7. Alternative splicing and viral infections
8. Alternative splicing and other disorders
9. Integrative multiomics: An approach to understanding alternative splicing
10. Recent therapeutic approaches involving alternative splicing
11. Splice-switching strategies for neurodegenerative diseases
