Full Description
Handbook of Melatonin-Based Therapy and its Applications provides pharmaceutical researchers and health professionals with a comprehensive reference on the applications of melatonin in the therapeutic setting. Succinct, meticulously organized, and expertly written, this book addresses all essential aspects. It starts with an overview of safe use of melatonin, translational aspects, and its prospection. The next section of the book covers a variety of clinical applications, including dosage, pharmacokinetics and pharmacodynamic profiles, toxicity, and principles of action. The chapters in this section cover applications to both adults and pediatric patients suffering from conditions like skin cancers, GI issues, psychiatric, hepatic and ocular conditions.
This is a comprehensive resource for pharmaceutical scientists and health professionals involved in developing therapies and applying them to patients. Researchers in the fields of medicine, biology, neuroscience, and pharmacology conducting studies related to melatonin-based will benefit from insights into the latest research findings, clinical trials, and therapeutic approaches.
Contents
1. Physiology and Safety of melatonin
2. Translational melatonin in preclinical models
3. Melatonin and COVID-19
4. Obtaining phytomelatonin and other bio(logical)-melatonin: sources and therapeutic applications
5. Melatonin as a Therapy for Neonatal Encephalopathy: The journey to clinical trials
6. Melatonin Gastroprotection by melatonin: an emerging concept and underlying mechanisms
7. Melatonin as a therapeutic in the skin
8. The use of melatonin in oxidative stress of the newborn
9. Synergistic impact of melatonin on colorectal cancer
10. Melatonin in Oncology: Unveiling its Potential in Prostate Cancer
11. The use of melatonin in pediatric perioperative care
12. Exploring melatonin as a therapeutic approach for mustard vesicants
13. Epigenetic Modulation by Melatonin: Clinical Implications and Therapeutic Prospects
14. Why Melatonin Administration might be harmful during the mounting of a defense response
15. New galenic formulations of melatonin and therapeutic applications
16. Melatonin, sleep and mood disorders
17. Melatonin and neurodegenerative diseases
18. Melatonin and autism spectrum disorders
19. Melatonin and andrology
20. Melatonin and hepatic injury
21. Melatonin treatment against experimental optic Neuritis and glaucoma
