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Full Description
Antidiabetic Drug Discovery from Natural Products provides up-to-date and in-depth information, practical understanding, and guidance in a comprehensive, systematic and easy-to-understand manner to scientists, researchers, and graduate students on important and emerging biochemical topics related to current antidiabetic drug discovery research. This book analyzes and studies natural active substances and their medicinal chemistry in preventing and treating diabetes and its complications. It covers a wide range of critical issues to assist chemists in the discovery and development of safer, more affordable treatments, from identifying promising leads from medicinal plants to the extraction and synthesis of bioactive compounds.
Following an introduction to bioactive chemical compounds from plants with antidiabetic effects, the book describes the discovery and extraction of antidiabetic drugs and antioxidants from natural sources. It also examines antidiabetic plants before delving deeper into the chemistry behind major medicinal substances and their derivatives like Mangiferin and Resveratrol, discussing both current and prospective uses.
Contents
Section 1: Putative antidiabetic drugs
1. Natural products in antidiabetic drug discovery: Historical perspective
2. Natural products in antidiabetic drug discovery: advances and opportunities
Section 2: Plant bioactives and their antidiabetic potential
3. Antidiabetic flavonoids from plant source
4. Antidiabetic terpenoids from plant source
5. Antidiabetic potential of plant alkaloids
6. Antidiabetic carbohydrates from natural sources
7. Antidiabetic potential of glycosides
8. Antidiabetic potential of tannins
9. Biological macromolecules as antidiabetic agents
10. Antidiabetic drugs from fungi
11. Antidiabetic secondary metabolites from marine source
Section 3: Pharmacological mechanism
12. Screening of antidiabetic drugs: in-vitro approaches
13. Animal models for screening of antidiabetic drugs from natural sources
14. Molecular Mechanisms of secondary metabolites as antidiabetic agents
15. Network pharmacology approach for antidiabetic drugs from natural sources
Section 4: Natural antidiabetics: Nature to clinic and market
16. Recent advances in natural antidiabetics
17. Antidiabetic drugs: Marketed formulations and case studies
18. Antidiabetic drugs: Patent case studies
19. Natural antidiabetic herbs and drug interactions
