Reconstructive Transplantation and Regenerative Surgery : The New Frontier (Regenerative and Transplant Medicine)

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Reconstructive Transplantation and Regenerative Surgery : The New Frontier (Regenerative and Transplant Medicine)

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  • 製本 Hardcover:ハードカバー版/ページ数 300 p.
  • 言語 ENG
  • 商品コード 9780443300844

Full Description

Reconstructive Transplantation and Regenerative Surgery: The New Frontier, Volume Three in the Regenerative and Transplant Medicine series—explores this transformative discipline. This integration aims to overcome the limitations of traditional vascularized organ and tissue transplantation, offering innovative solutions through cutting-edge techniques. As regenerative surgery continues to evolve, this volume serves as a comprehensive resource, highlighting the latest advancements in graft immunomodulation, neuroregeneration, gene editing, diagnostic imaging, ischemia mitigation, and graft preservation. Authored by leading experts, this volume delves into crucial topics such as cell therapies, immunobiologics, neurobiologics, and targeted therapeutic strategies like local immunosuppressive implants and immunocloaking.

It also covers cutting-edge diagnostic approaches, including non-invasive molecular imaging, nanotheranostics, and multimodal surveillance techniques. By addressing critical challenges in transplantation and regeneration, this book is an essential reference for surgeons, clinicians, trainees, scientists, and academics dedicated to advancing the field.

Contents

Part I - The Cutting Edge
The World's Largest Single Center Experience in Face Transplantation
Viola Stogner, Yale U, New Haven
Laryngotracheal Transplantation—Evolution and Experience
Eric Genden, Mount Sinai Medical Center, NY

Part II - Unique Considerations and Emerging Indications
Lower Limb Transplantation - Pre-Clinical Insights and Patient Considerations
Anvesh Kodali, Advocate Health
Penile Transplantation - Experience and Emerging Indications
Jana Ramu, Advocate Health
Whole Eye Transplantation - Knowns and Unknowns
Mariana Mayorquin, National Autonomous University of Mexico, Mexico City

REGENERATIVE SURGERY

Part III - Targeted Technologies and Therapies
In-Situ, Implantable and Locally Injectable Drug Delivery - State of the Art
Praveen Vemula, INSTEM
Smart Sensors for Graft Health Monitoring
Atul Sharma, Tufts, Boston
Opportunities in Covalent Tissue Modification for Graft-localized Drug Release
Bob Kane, Waco, Texas

Part IV - Cellular and Regenerative Therapies
Cell Therapy and Immune Tolerance: State of the Art and Potential Applications in Reconstructive Transplantation
David Leonard, Leeds, UK
Gene Editing Strategies for Immunomodulation
Zeynep Demir, Advocate Health
Part V- Graft Preservation
Novel Oxygen Carrier Perfusates for Transplant Applications
Jelena Janjic, Pittsburgh
Preservation Technologies in Reconstructive Transplantation: Lessons From Solid Organ Experience
Varun Kopparthy, BMI

Part VI - Tissue Engineering and Regenerative Biomaterials
Tracheal Tissue Engineering
Siba Haykal, Yale U.
Thymus Tissue Engineering
Gauri Kulkarni, Advocate Health
Customized Bioresorbable Implants for Bone Fixation in Reconstructive Transplantation
Prashant Kumta, University of Pittsburgh

Part VII - Special Populations in Reconstructive Transplantation
Hand and Face Transplantation in Teens and Young Adults - Unique Considerations
Mary Brooks Hall, Wake Forest University

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