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Full Description
Protein Misfolding Diseases, delves into the intricate molecular mechanisms behind a class of devastating disorders caused by abnormal protein folding. This comprehensive book explores the pathophysiology, diagnostic challenges, and therapeutic strategies associated with a spectrum of protein misfolding diseases, including neurodegenerative conditions like Alzheimer's, Parkinson's, and prion diseases, as well as systemic amyloidoses. From unraveling the underlying protein aggregation processes to discussing cutting-edge research on disease-modifying therapies, this book provides a multidisciplinary perspective on understanding and combating protein misfolding diseases. With contributions from leading experts in the field, it serves as a valuable resource for researchers, clinicians, and students seeking to deepen their knowledge of these complex and challenging disorders.
Contents
1. Protein misfolding in hemophilia
Bilgimol Chumappumkal Joseph, Nicca Falah, Juan Andres De Pablo-Moreno, Dana H Simmons and Annette von Drygalski
2. TBD
Sarita Montaño
3. TBD
Sreejith Madhavankutty
4. Characterizing Protein Misfolding: Inside and Out
Amritangshu Chakravarty
5. TBD
Krishnamurthy Nakuluri and Vani Gowru
6. TBD
Shahab Uddin, Abdul Ansari, Aamir Ahmad, Lubna Therachiyil, Gazala Anamangadan, Manel Sadok and Hesham M Korashy
7. Longitudinal plasma proteome of vaccinated individuals reveals altered factors associated with blood coagulation and immune responses
Aamir Ahmad
8. TBD
Muzafar Ahmad Macha
9. TBD
Manzoor A. Mir Sr.
10. Heat Shock proteins (HSPs) as chaperones for Oncogenesis
Mayank Singh
11. TBD
Ajaz Ahmad Bhat
12. Protein Misfolding and Cancer: Molecular Insights and Future Perspectives
Sireesha V. Garimella and Geethika Ishani Makka
13. Proteostasis and Pathogenesis: Unraveling the Complexity of Protein Misfolding Disorders
Biplab Singha, Tripti Nair, Ditsa Sarkar, Sumit Murmu and Rahul Rawat
14. TBD
Surbhi Sharma
15. TBD
Rakesh Kumar I
16. Small molecule inhibitors targeting α-synuclein aggregation: Progress and future outlook
Tanveer Ali Dar Sr., Ishfaq Bashir Hajam, Ishfaq Ahmad Ahanger and Umar Rasool
17. Chaperone Machinery in Neurodegeneration: A Spotlight on Protein Misfolding Diseases
Arpit Mehrotra, Abhilasha Sood, Deepak Kumar Sharma, Madhumita Dey and Arpit Tyagi
18. Title yet to decide
Shivani Mittal
19. Calpain- mediated proteolytic cleavage
Subashchandrabose Chinnathambi, Nagaraj Rangappa and Tushar Dubey