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Full Description
The Biology of Ageing: From Hallmarks to Drugs provides a series of reviews covering multiple aspects of the translational pipeline as interventions in the biology of ageing itself become a clinical reality. New chapters cover Cellular senescence and NAD+: what are the links?, Biomarker for ageing: potential and pitfalls, What chemists offer to ageing research, You are what you eat - or are you? Exploring dietary versus topical anti-oxidants in skin ageing, Clinical trials: A simple guide for gerontologists, Towards an ethical framework for geroscience, and more.
The book explores links between known ageing mechanisms and new interventions, agents and actions at the nutraceutical-drug divide, the challenges and opportunities provided by biomarkers and chemistry- biology interface and lastly the ethical and operational challenges of clinical trials in the age of translational geroscience.
Contents
Preface
Richard Faragher
1. You are what you eat—Or are you? Exploring dietary versus topical antioxidants in skin aging
Oliver Dillon, Damon Bevan, Jelena Gavrilovic
2. Clinical trials: A simple guide for gerontologists
Simona Reed
3. Toward an ethical framework for geroscience?
Richard Faragher
4. Selective autophagy-driven senescence as a barrier to tumorigenesis: Arriving at the destination through an alternative path
Andreas Goutas, Varvara Trachana
