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Full Description
The Biology of Ageing: From Hallmarks to Drugs provides a series of reviews covering multiple aspects of the translational pipeline as interventions in the biology of ageing itself become a clinical reality. New chapters cover Cellular senescence and NAD+: what are the links?, Biomarker for ageing: potential and pitfalls, What chemists offer to ageing research, You are what you eat - or are you? Exploring dietary versus topical anti-oxidants in skin ageing, Clinical trials: A simple guide for gerontologists, Towards an ethical framework for geroscience, and more.
The book explores links between known ageing mechanisms and new interventions, agents and actions at the nutraceutical-drug divide, the challenges and opportunities provided by biomarkers and chemistry- biology interface and lastly the ethical and operational challenges of clinical trials in the age of translational geroscience.
Contents
Preface
Richard Faragher
1. Cellular senescence and NAD+: what are the links?
Sophia Quigley
2. Biomarker for ageing: potential and pitfalls
Lynne Cox
3. What chemists offer to ageing research
Richard Hartley
4. You are what you eat - or are you? Exploring dietary versus topical anti-oxidants in skin ageing
Oliver Dillon
5. Clinical trials: A simple guide for gerontologists
Simona Reed
6. Towards an ethical framework for geroscience
Richard Faragher