Full Description
Biochemical and Molecular Pharmacology in Drug Discovery comprises fundamental biochemical and molecular aspects of drug discovery and basic understanding of modern drug discovery approaches, along with certain key topics related to molecular pharmacology of drugs and therapeutics. The book explains the phenomena of drug-target interactions, considering different biochemical systems and cellular strategies. With the advent of technologies, current advances, and research trends move toward molecular and/or target-based drug design and discovery. Through this book, readers will gain skills and knowledge with a thorough understanding of the subject of biochemical and molecular pharmacology in a comprehensive and systematic manner.
Molecular pharmacology has gained significant momentum among researchers, scientists, and academicians because of its increasing interest in drug discovery research across the globe. Molecular pharmacology involves a fundamental understanding of drug actions at the molecular level with the help of several tools and techniques of biochemical and molecular biology.
Contents
1. Structure and Functions of Biomolecules
2. Pharmacokinetics and Pharmacodynamics
3. Overview of Drugs and Drug Targets
4. Nucleic Acids as Drug Targets
5. Molecular Cloning of Drug Targets
6. Pharmacogenetics and pharmacogenomics in drug discovery
7. Drug-Receptor Interactions
8. Enzymology in Drug Discovery
9. Targeting Epitranscriptomics for Novel Drug Development
10. Applications of molecular pharmacology in drug discovery
11. Fundamentals of drug design and discovery
12. Fundamental Approaches of Drug Discovery
13. Enzyme Inhibitors: Design of Kinase Inhibitors as anticancer drugs
14. Reverse Pharmacology and Drug Repositioning in Drug Discovery
15. Bioinformatics and CADD Approaches in Drug Discovery
16. Artificial Intelligence-based protein structure prediction and systems biology-guided smart drug screening
17. Recombinant DNA Technology and Gene Therapy
18. Gut-Health Pharmacology: Integrating Microbiota Insights with Natural Product Therapies
19. Neuropharmacology and Neurotherapeutics: Advancing the Understanding and Treatment of Neurological Disorders
20. Molecular Oncobiology and Cancer Chemotherapeutics
21. Molecular Inflammopharmacology and Therapeutics
22. Molecular Cardiopharmacology and Therapeutics-I
23. Molecular Cardiopharmacology and Therapeutics-II
24. Molecular Endocrine Pharmacology and Therapeutics
25. Molecular Viral Infections and Anti-viral Therapeutics
