臨床における分子病理学<br>Molecular Pathology in Clinical Practice

臨床における分子病理学
Molecular Pathology in Clinical Practice

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  • 製本 Hardcover:ハードカバー版/ページ数 604 p./サイズ 188 illus.
  • 言語 ENG
  • 商品コード 9780387332260

基本説明

An authoritative, comprehensive textbook that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular testing.

Full Description


This authoritative textbook embodies the current standard in molecular testing for practicing pathologists, and residents and fellows in training. The text is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management. Discussion of each diagnostic test includes its clinical significance, available assays, quality control and lab issues, interpretation, and reasons for testing. Coverage extends to HIV, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage, and much more. Includes 189 illustrations, 45 in full-color. This textbook is a classic in the making and a must-have reference.

Contents

Basics of Molecular Biology.- Basics of Molecular Biology.- Molecular Pathology Methods.- Molecular Pathology Methods.- Genetics.- Genetic Counseling.- Pedigree Analysis and Risk Assessment.- Bayesian Analysis.- Developmental Disabilities.- Neuromuscular Diseases.- Molecular Genetic Testing for Metabolic Disorders.- Fibroblast Growth Factor Receptor-Related Skeletal Disorders.- Cystic Fibrosis.- Deafness.- Coagulation Disorders.- Hematologic Disorders: Hemochromatosis, Hemoglobinopathies, and Rh Incompatibility.- Cardiovascular Disease.- Neurodegenerative Disorders.- Skin and Connective Tissue Disorders.- Inherited Cancers.- Inherited Breast Cancer.- Familial Adenomatous Polyposis and Turcot and Peutz-Jeghers Syndromes.- Hereditary Nonpolyposis Colorectal Cancer.- Multiple Endocrine Neoplasia Syndromes.- The Neurofibromatoses.- TP53 Mutation and Li-Fraumeni Syndrome.- von Hippel-Lindau Disease.- Solid Tumors.- Breast Cancer.- Urothelial Carcinoma.- Sarcomas.- Gliomas.- Molecular Detection of Occult Tumor Cells.- Microarray Studies (Beyond Histology).- Neoplastic Hematopathology.- Acute Myeloid Leukemia.- Acute Lymphoblastic Leukemia.- B-Cell Lymphomas.- T-Cell Lymphomas.- Lymphoproliferations of Immunodeficiency.- Myeloproliferative Disorders and Myelodysplastic Syndromes.- Infectious Diseases.- Human Immunodeficiency Virus Type 1.- Hepatitis B and C Viruses.- Viral Infections in Transplant Patients.- Viral Infections of the Central Nervous System.- Sexually Transmitted Diseases.- Respiratory Pathogens.- Bacterial Pathogens.- Mycobacterial Infections.- Identity Testing.- Forensic DNA Typing.- Parentage and Relationship Testing.- Assessment of Chimerism in the Setting of Allogeneic Hematopoietic Cell Transplantation.- Specimen Identification Through DNA Analysis.- HLA Typing.- Molecular HLA Typing.- Laboratory Management Issues.- Molecular Pathology Laboratory Management.- From Research to Clinical Practice.

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