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Full Description
Due to their medicinal activity and potential use as synthetic starting materials, studies on beta-lactams have increased significantly. This unique volume takes readers on a tour de force from the concept of antibiosis to the serendipity of antibiotics, evolution of beta-lactam development, and molecular biology of antibiotic resistance. These areas of research have culminated in a deeper understanding of microbiology, particularly in the area of bacterial cell wall synthesis and recycling. Considerable work has been performed by chemists and biologists to continue updating their findings about beta-lactam synthesis.
Features:
Stereoselective synthesis of monocyclic, bicyclic, and polycyclic beta-lactams
Microwave, ultrasound, and solid support-mediated preparation of beta-lactams
Diverse medicinal activities including anticancer activities of beta-lactams and products obtained from them
Nanoparticles, artificial intelligence, and dipole moments in beta-lactam science
Synthesis and mechanism of formation of polyaromatic beta-lactams
Contents
1. Beta-Lactams: Classifications, Biogenesis, Physical Characteristics and Medicinal Activities. 2. Monocyclic Beta-Lactams: Stereocontrolled Synthesis by Diverse Methods. 3. Polycyclic Beta Lactams: Synthesis by Diverse Methods. 4. Polyaromatic Beta Lactams: Synthesis and Anticancer Activities. 5. Microwave and Ultrasound in Beta-Lactam Chemistry. 6. Solid Support-Mediated Beta Lactam Synthesis. 7. Mechanism of Beta-Lactam Synthesis by Cycloaddition Reaction. 8. Beta Lactams as Synthons for Diverse Heterocycles. 9. Medicinal Activities of Beta Lactams as Antibacterials and Their Mechanism of Action. 10. Antibacterial Effects of Beta-Lactam Antibiotics with Nanoparticles. 11. The Effects of Dipole Moments on the Biological Activities of Diverse Beta Lactams. 12. Artificial Intelligence on Beta-Lactam Research.