Full Description
First Published in 1994, Introduction to In Vitro Cytotoxicology examines in vitro cytotoxicology, which offers new methodologies to toxicity testing. This important new discipline of modern toxicology is gaining increased acceptance as a viable alternative to traditional testing methods. The text discusses the application of in vitro cytotoxicology to toxicity testing and human risk assessment, and it analyzes the advantages and limitations of the tests performed under scientific and regulatory conditions. The book also reviews the optimum utilization of certain tests for specific groups of chemicals relevant to validation programs currently in progress. This book is a useful reference tool for students, researchers, and practitioners interested in academic, industrial, and regulatory toxicology; environmental health; cell biology; pharmacology; dentistry; or human and veterinary medicine.
Contents
Cell Culture Methodology and Its Application to In Vitro CytotoxicologyMechanisms of CytotoxicologyCellular Methods of General ToxicityCellular Methods of Target-Organ ToxicityCellular Methods of Local ToxicityCellular Methods of TeratogenicityCellular Methods of Immune FunctionPharmacokinetic Studies in Cellular SystemsCellular Methods of Genotoxicity and Carcinogenicity, T.W. SawyerExperimental Design and StatisticsStandardization and Validation, B. Ekwall, F.A. BarileCell Culture or Animal Toxicity Tests? Or Both?Index.
