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Full Description
G Protein-Coupled Receptors, Part B, Volume 195 represents the largest class of cell H103 surface proteins that have intricate involvement in nearly every physiological process in our body. Approximately one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. Sections in this volume include Adhesion G protein-coupled receptors: Structure and functions, Molecular and cellular mechanisms underlying brain region-specific cannabinoid receptor modulation by estradiol across the rodent estrus cycle, Probing the orphan receptors: Tools and directions, Asymmetric activation of Class C GPCRs, Common and selective signal transduction mechanisms of GPCRs, and much more.
Contents
Preface
Arun K. Shukla
1. Adhesion G protein-coupled receptors: Structure and functions
Doreen Thor and Ines Liebscher
2. Molecular and cellular mechanisms underlying brain region-specific cannabinoid receptor modulation by estradiol across the rodent estrus cycle
Hye Ji J. Kim, Ayat Zagzoog, Tallan Black, Sarah L. Baccetto and Robert B. Laprairie
3. Probing the orphan receptors: Tools and directions
Luca Franchini and Cesare Orlandi
4. Asymmetric activation of Class C GPCRs
Hongnan Liu, Yanjun Li and Yang Gao
5. Common and selective signal transduction mechanisms of GPCRs
Berkay Selçuk and Ogun Adebali
6. Appreciating the potential for GPCR crosstalk with ion channels
Amy Davies and Alejandra Tomas
7. Recent advances in calcium-sensing receptor structures and signaling pathways
Caroline M. Gorvin
8. Structural insights into promiscuous GPCR-G protein coupling
Angela Carrión-Antolí, Jorge Mallor-Franco, Sandra Arroyo-Urea and Javier García-Nafría
9. Opioid signaling and design of analgesics
Barnali Paul, Sashrik Sribhashyam and Susruta Majumdar
