Full Description
Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.
Contents
Section A: SARS-CoV-2 and COVID-19: Introductory chapters and setting the scene
1. Coronavirus disease 2019 (COVID-19) pandemic in context: Systemic effects
2. Early warning of SARS-CoV-2 infection
3. Mobile phones and their use to study dynamics of the COVID-19 pandemic
Section B: Structure, transmission and avoidance
4. Cis regulatory elements: A novel communication route between the host cell and the SARS-CoV-2 genome
5. SARS-CoV-2 ORF8: Structure, evolution, molecular function, and its contribution to the
pathogenicity of the virus
6. SARS-CoV-2 spike protein binding ligands and its application in COVID-19 therapeutics
7. SARS-CoV-2 bulldozes the autophagy pathway and unhinges mitochondrial quality control
thereby driving neurodegeneration—A hypothesis
8. The Omicron variant of SARS-CoV-2
9. Monitoring SARS-CoV-2 spread in hospitals
10. Computational analysis of mutations in SARS-CoV-2 variants spike protein and protein
interactions
11. Airborne transmission of SARS-CoV-2
12. Reducing transmission of SARS-CoV-2 with face masks: Its potential protective effects
13. Digital twin of ventilation system against COVID-19 transmission and infection risk
14. Pets and SARS-CoV-2: What is their role in the epidemiology of the disease?
15. SARS-CoV-2 transmission in dental practice
16. SARS-CoV-2 compared with influenza and respiratory syncytial virus in terms of vertical
transmission
17. Reducing droplets and aerosols in the surgical setting and applications to the COVID-19
pandemic
18. SARS-CoV motion dynamics: Linking in droplet size
19. Ventilation and airborne particles in classrooms: Implications for the COVID-19 pandemic
20. Indoor transmission of the SARS-CoV-2 virus through aerosols emitted by e-cigarettes
Section C: Impact and effects
21. The Impact of COVID-19 on first responders
22. COVID-19 and suspected drug-induced liver injury
23. Pulmonary fibrosis in COVID-19
24. The effect of SARS-CoV-2 infection on cancer: Clinical correlation and
potential pathological mechanism
25. Severe SARS-CoV-2, plateletendothelium interactions, and cardiovascular injury
26. Cardiometabolic syndrome and COVID-19: Pathophysiological aspects
27. COVID-19 and type 1 and 2 diabetes: An overview
28. COVID-19 and older adults: An overview
29. COVID-19 and male fertility
30. COVID-19 and obesity: An overview
Section D: Treatments, strategies, and vaccines
31. COVD-19 vaccines and their impact: An overview
32. Exploring the promise of COVID-19 vaccines: A review of preclinical studies
33. Drugs actively being investigated for use in COVID-19
34. The biology of neutralizing antibody therapy with REGEN-COV
35. The intensive care unit and percutaneous tracheostomy in patients with coronavirus disease
2019
36. Cardiac effects of drugs and vaccines used to treat and prevent COVID-19
37. COVID-19 pandemic and isolation: Impact on sleep
38. Strategies in the COVID-19 pandemic: Disinfection of gloved hands
39. In silico studies on established antivirals on SARS-CoV-2 RNAdependent RNA polymerase
40. The COVID-19 cytokine storm and its immunomodulatory treatment
41. Safety and efficacy of nebulization for reducing the intensity of viral load and clinical manifestations in patients with COVID-19
Section E: Detection and biomarkers
42. Bronchoalveolar lavage (BAL) and use in detection of SARS-CoV-2
43. SARS-CoV-2 testing and vaccination among people who use drugs
44. Homocysteine as a biomarker in COVID-19
45. Assessment of smell and taste in COVID-19
46. S-gene analysis: RT-PCR and Sanger sequencing applied to SARS-CoV-2 virus
47. False-negative results in screening for SARS-CoV-2
48. Sample pooling and SARS-CoV-2 assays
49. Biomarkers of invasive mechanical ventilation in obesity and metabolic syndrome in patients
with COVID-19
Section F: Case studies with mini review
50. Hypoxia and heart-lung interactions in COVID-19: The significance of right heart dysfunction and shunt
51. Ulnar nerve dysfunction as COVID-19 sequelae
52. Case study: Coronavirus disease 2019 and acute kidney injury
53. Case study: The detection and treatment of a pneumothorax in a patient with coronavirus disease 2019 pneumonia
54. Proposal and demonstration of a survey method for the prevention of airborne transmission: Case studies in healthcare and welfare facilities
Section G: Resources
55. Recommended resources for the features, transmission, and detection of coronavirus disease
2019 (COVID-19)
