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Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats. The book discusses how advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies that have paved the way for next-generation immunoassays.
Revised and updated, the second edition of Handbook of Immunoassay Technologies: Approaches, Performances, and Applications covers all the relevant, timely, and important developments in the field. This edition offers new content on topics such as antibody production for immunodiagnostics, multiplex immunoassays, chemiluminescent immunoassays, immunoassays for newborn screening, and immunoassays of viruses like SARS-CoV-2, HIV, Ebola, and Hepatitis C. The addition of these new topics as well as up-to-date content make the second edition a valuable and comprehensive resource on immunoassays.
Contents
1. Immunoassays: an overview
Sandeep K. Vashist and John H.T. Luong
2. Antibody immobilization and surface functionalization chemistries for immunodiagnostics
Sandeep K. Vashist and John H.T. Luong
3. Monoclonal antibody generation by phage display: history, state-of-the-art, and future
Christian Hentrich, Francisco Ylera, Christian Frisch and Achim Knappik
4. Bioanalytical requirements and regulatory guidelines for immunoassays
Sandeep Kumar Vashist and John H.T. Luong
5. Enzyme-linked immunoassays
Sandeep K. Vashist and John H.T. Luong
6. Chemiluminescent immunoassays (CLIA)
Sandeep K. Vashist and John H.T. Luong
7. Lateral flow immunoassays
Aart van Amerongen and Marjo Koets
8. Paper-based immunoassays
Zhi Liu, Jie Hu, Zhiguo Qu and Feng Xu
9. Acoustic wave-based immunoassays
Aristea Grammoustianou and Electra Gizeli
10. Interferometry-based immunoassays
P. Petrou, E. Makarona, S. Kakabakos, G. Koukouvinos, K. Misiakos and I. Raptis
11. Nanomaterial- and micromaterial-based immunoassays
Minli You, Zedong Li, Penghui Zhang, Dan Bai, Min Lin and Feng Xu
12. Microcantilever-based sensors
Sandeep K. Vashist and John H.T. Luong
13. Quartz crystal microbalance-based sensors
Sandeep K. Vashist and John H.T. Luong
14. Electrochemical immunosensors fundamentals and applications in clinical diagnostics
Kuldeep Mahato, Suveen Kumar, Ananya Srivastava, Pawan K. Maurya, Renu Singh and Pranjal Chandra
15. Lab-on-a-chip immunoassays
Sandeep K. Vashist and John H.T. Luong
16. Smartphone-based immunoassays
Sandeep K. Vashist and John H.T. Luong
17. Multiplex immunoassays
Sandeep K. Vashist and John H.T. Luong
18. Immunoassays for newborn screening
John H.T. Luong and Sandeep K. Vashist
19. Biotin interference in immunoassays and strategies to tackle it
John H.T. Luong and Sandeep K. Vashist
20. In vitro diagnostic immunoassays for SARS-CoV-2
Sandeep K. Vashist and John H.T. Luong
21. Immunoassays of human immunodeficiency virus (HIV)
John H.T. Luong
22. Immunoassays of hepatitis C virus (HCV)
John H.T. Luong and Sandeep K. Vashist
23. Immunoassays for Ebola virus disease
John H.T. Luong
24. Immunoassays of botulism neurotoxins (BoNTs) of Clostridia
John H.T. Luong
25. Immunoassays of biological warfare agents
John H.T. Luong
26. Lateral flow immunoassays with improved detection sensitivity
John H.T. Luong and Sandeep Kumar Vashist
27. Immunoassays: future prospects and possibilities
Sandeep Kumar Vashist and John H.T. Luong
