Full Description
Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ꞵ-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology.
Contents
1. Introduction: state of the art, new challenges, and opportunities for drug delivery and its application
2. Drug delivery application: an outlook on past and present technologies
3. General mechanisms of drug loading and sustained release
4. Supramolecular hydrogels as drug delivery systems for nerve regeneration and wound healing
5. Molecularly imprinted polymeric carriers for controlled drug release
6. Engineered extracellular vesicles as drug delivery systems for the next generation of nanomedicine
7. Polyelectrolyte multilayer films for cancer therapy
8. Porous metal9. Stimulus-responsive liposomes as smart nanocarriers for drug delivery applications
10. Hybrid platforms for drug delivery applications
11. Self-nanoemulsifying drug delivery systems with bioavailability potential
12. Graphene-based nanomaterials for targeted drug delivery and tissue engineering
13. Bionanocomposites as a new platform for drug delivery systems
14. Nanotube platforms for effective drug delivery applications
15. Biodegradable polymeric nanoparticle drug for oral delivery applications
16. Delivery of radiopharmaceuticals and theranostic agents: targeted alpha therapy
17. Controlled drug release and drug delivery applications from mesoporous nanoparticles
18. Porous nanostructured metal oxides as potential scaffolds for drug delivery
19. Thin films as an emerging platform for drug delivery
20. Modeling and simulation in drug delivery
21. In-vivo drug release studies
22. Toxicity measurement and toxicity studies of drug delivery
23. Nasal and pulmonary routes of drug delivery
24. "Gene therapy”: ethical and regulatory issues
25. New challenges in drug discovery
