Full Description
Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals.
Contents
1. The aging: introduction, theories, principles and future prospective
Shabnam Shabir, Mahendra Pratap Singh
2. Brief description of aging in different levels as cellular, tissues, and organs
Anuradha Venkatakrishnan Chimata, Prajakta Deshpande, Amit Singh
3. Brief about hallmarks of aging
Josephine Esposto and Vyshnavy Balendra
4. Overview of various anti-aging strategies
Dhiraj Kumar and Faiyaz Ahmad
5. Elimination of damaged cells-dependent anti-aging strategy
Rayees Ahmad Naik, Vinodinee Dubey, Roshni Rajpoot, Debabrata Dash, Nidhi Gupta and Raj Kumar Koiri
6. Telomerase reactivation for anti-aging
TS Gopenath, Shreya Shreshtha and Kanthesh M. Basalingapa
7. Epigenetic drugs based on anti-aging approach
Tarun Minocha, Namrata Dwivedi, Chetan Panda, Anamika Misra, Barsha Baisakhi Nayak, Sanjeev Kumar Yadav, Hareram Birla and Sandeep K. Singh
8. Activation of chaperons and proteolytic system: emerging methods for anti-aging drug development
Neha Gogia, Victor Olmos, Fatema Haidery, Kimberly Luttik, Leon Tejwani, Janghoo Lim
9. Dietary restriction and mTOR and IIS inhibition: the potential to anti-aging drug approach
Sing-Hua Tsou
10. Anti-Aging Drugs, Candidates, and Food Supplements- The journey so far
Yodhaanjali JR, Rithwick Surya, Sumukha KC, Harini G, Gouri Deshpande, Chandan S,Raghu Ram Achar
11. Role of AMPK and Sirtuins as anti-aging proteins
Manjula Ramu, Sonali Vishal and Neha Gogia
12. Mitophagy and Mitohormetics: promising anti- aging strategy
Chih Li Lin
13. Clearance of senescent cells: potent anti-aging approach
Jacques Ferreira and Alex Deamer
14. Stem cell-based therapy as antiaging prospective
Sumaira Yusuf, Mahendra P. Singh
15. Anti-inflammatory therapy as a game changer towards anti-aging
Dr. Naveen Shivavedi, Anshul Shakya, Bedanta Bhattacharjee and Bhargab Deka
16. Invertebrate model organisms for aging research
Arvind Kumar Shukla, Andrew Scott and Edward Giniger
