Full Description
Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition provides basic scientists a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases. Topics include developmental, autoimmune, central, and peripheral neurodegeneration, infectious diseases, and diseases of higher function.
Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more.
Contents
Section I: Introductions
1. A Clinical Neuroscientist's Overview of Disorders of the Brain
2. Disease around the world
Section II. Developmental Disorders
3. Introduction
4. Developmental Disabilities and Metabolic Disorders
5. Attention Deficit/Hyperactivity Disorder
6. Down Syndrome: A Model for Chromosome Abnormalities
7. Autism Spectrum Disorder
8. Rett Syndrome: From the Involved Gene(s) to Treatment
9. Fragile X-Associated Disorders
Section III. Diseases of The Peripheral Nervous System
10. Introduction
11. Myasthenia Gravis
12. Muscular Dystrophy
13. Peripheral Neuropathies
14. Diabetes and Cognitive Dysfunction, Catrina Sims-Robinson
Section IV. Diseases of the Central Nervous System and Neurodegeneration
15. Introduction
16. Spinal Cord Injury
17. Vascular Diseases of the Nervous System
18. Toxic/Metabolic Diseases of the Nervous System
19. Traumatic Brain Injury
19. Epilepsy
20. Amyotrophic Lateral Sclerosis
21. Parkinson Disease and Other Synucleinopathies
22. Huntington Disease
23. Alzheimer Disease
24. Cerebrovascular Disease - Stroke
25. Prion Diseases
Section V. Infectious and Immune-Mediated Diseases Affecting the Nervous System
26. Introduction
27. Role of Inflammation in Neurodegenerative Diseases
28. Role of Inflammation in Psychiatric Disease
29. Infections and Nervous System Dysfunction
30. Pathobiology of CNS Human Immunodeficiency Virus Infection
31. Emergent Viral infections of the Nervous System
32. Autoimmune and Paraneoplastic Neurological Disorders
33. Fibromyalgia and Chronic Fatigue
34. Multiple Sclerosis
Section VI. Diseases of Higher Function
35. Introduction
36. Disorders of Higher Cortical Function
37. Disorders of Frontal Lobe Function
38. Stress
39. Addictions
40. Sleep Disorders
41. Restless Legs Syndrome
42. Fear-Related Anxiety Disorders and Post-Traumatic Stress Disorder
43. Obsessive-Compulsive Disorder
44. Schizophrenia
45. Bipolar Disorder
46. Pain: From Neurobiology to Disease
47. Migraine
48. Depression and Suicide
Section VII. Diseases of the Nervous System and Society
49. Introduction
50. The Neurological and Psychiatric Consequence of Aging
51. Advances in Ethics for the Neuroscience Agenda
52. Burden of Neurological Disease
53. Stress, Health, and Disparities
54. The impact of isolation on brain health
