Full Description
Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms.
Contents
1. Gene suppressor and oncogenes
2. Implication of growth factor's genes in genitourinary cancers
3. Cytokines genes alterations
4. Proteomic analysis
5. Genetic diagnostics and prognostic biomarkers
6. Exosomes as diagnostic and prognostic tool
7. Metabolism defects
8. Clinical genomic relevance
9. Recent advances of immunotherapy
10. Modern therapeutic targets
