Full Description
Clinically focused and designed to provide a to-the-point overview, Glioblastoma, by Drs. Steven Brem and Kalil G. Abdullah, brings you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides neurosurgeons, medical-and-radiation oncologists, neuro-oncologists, neuropathologists, internal medicine physicians, and researchers with a dependable source of information on current treatment options, tumor recurrence, and patient care.
Evidence for current treatment options for de novo and recurrent glioblastoma, indications for local and topical therapies, immunotherapy, gene therapy, nanotherapy, small-molecule inhibition, electric tumor treating field stimulation, and antiangiogenic therapies and the role of Avastin.
Recent advances relating to tumor resection, such as stereotactic laser ablation, diffusion tensor imaging, and fluorescent markers.
Prognostic molecular and genetic markers and the impact of gene mutations on survival, as well as controversies relating to pseudo-progression.
Lessons learned from unsuccessful interventions, as well as the most promising aspects of future glioblastoma research and treatment.
Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Contents
Part I: Disease Origins and Context
The Story of Glioblastoma: History and Modern Correlates
Epidemiology of Glioblastoma and Trends in Glioblastoma Survivorship
The Molecular Pathogenesis of Glioblastoma
Diagnostic, Prognostic, and Predictive Biomarkers for Adult and Pediatric Gliomas in Clinical Practice
Multimodality Targeting of Glioma Cells
Part II: Standards of Medical and Surgical Treatment
Current Standards of Care in Glioblastoma Therapy
Radiographic Detection and Advanced Imaging of Glioblastoma
Principles and Tenets of Radiation Treatment in
Chemotherapeutics and Their Efficacy
Anti-angiogenic Therapy for Glioblastoma
Recurrent Glioblastoma
Principles of Surgical Treatment
Awake Craniotomy for Glioblastoma
Intraoperative Imaging of Glioblastoma
Minimally Invasive Targeted Therapy for Glioblastoma Laser Interstitial Thermal Therapy (LITT)
Local and Topical Treatment of Glioblastoma
Tumor Treating Electric Fields for Glioblastoma
Part III: Scientific Advances, Future Directions, and Socioeconomic Considerations
Brain Plasticity and Reorganization Before, During, and After Glioma Reseaction
Genetically modified T-cell therapy for glioblastoma
Early Detection of Glioblastoma
Health-Related Quality of Life and Neurocognitive Functioning after Glioblastoma Treatment
Socioeconomics and Survival
National and Global Economic Implications of Glioblastoma
Lessons Learned: Clinical Trials and Other Interventions for Glioblastoma
