Stability of Protein Pharmaceuticals : Pt B : in Vivo Pathways of Degradation and Strategies for Protein Stabilization (Pharmaceutical Biotechnology,)

Ahern, Tim J. (EDT)/ Manning, Mark C. (EDT)/ Ahern, Tim J.

Plenum Pub Corp（1992/11発売）

• 製本 Hardcover:ハードカバー版／ページ数 300 p.
• 言語 ENG
• 商品コード 9780306441530
• DDC分類 615.3

基本説明

Part B explores protein degradation occuring in vivo during protein synthesis in cells, examines the isolation and purification of proteins, details protein use in organisms, and reviews techniques to enhance protein stability.

Full Description

Part B explores protein degradation occuring in vivo during protein synthesis in cells, examines the isolation and purification of proteins, details protein use in organisms, and reviews techniques to enhance protein stability.

Contents

Improper Glycosylation and the Cellular Editing of Nascent Proteins; D.A. Cumming. Protein Aggregation In Vivo; R. Wetzel. Pathways of Intracellular Protein Degradation in Eukaryotic Cells; T.S. Olson, et al. Effects of Aging on Proteins; R.W. Gracy. Engineering Dramatic Increases in the Stability of Subtilisin; P.N. Bryan. Increased Stability of Mutant Forms of Yeast Cytochrome c; D.R. Hickey, et al. Introduction to Formulation of Protein Pharmaceuticals; M.A. Hanson, S.K.E. Rouan. PEG Modified Proteins; G.E. Francis, et al. Stabilization of Protein Structure by Solvent Additives; S.N. Timasheff. Heat-Shock Proteins and their Potential Uses for Pharmaceutical Protein Production in Microorganisms; J.M. McCoy. Index.