細胞死と生死の進化論的起源<br>The Evolutionary Origins of Life and Death

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細胞死と生死の進化論的起源
The Evolutionary Origins of Life and Death

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  • 製本 Hardcover:ハードカバー版/ページ数 232 p.
  • 言語 ENG
  • 商品コード 9780226747620
  • DDC分類 576.8

Full Description

The question of why an individual would actively kill itself has long been an evolutionary mystery. Pierre M. Durand's ambitious book answers this question through close inspection of life and death in the earliest cellular life. As Durand shows us, cell death is a fascinating lens through which to examine the interconnectedness, in evolutionary terms, of life and death. It is a truism to note that one does not exist without the other, but just how does this play out in evolutionary history? These two processes have been studied from philosophical, theoretical, experimental, and genomic angles, but no one has yet integrated the information from these various disciplines. In this work, Durand synthesizes cellular studies of life and death looking at the origin of life and the evolutionary significance of programmed cellular death. The exciting and unexpected outcome of Durand's analysis is the realization that life and death exhibit features of coevolution. The evolution of more complex cellular life depended on the coadaptation between traits that promote life and those that promote death. In an ironic twist, it becomes clear that, in many circumstances, programmed cell death is essential for sustaining life.

Contents

Foreword (by Eugene V. Koonin)
Preface
List of abbreviations
An introduction to the scientific study of life and death

Part One: The origin of life

1 Philosophical considerations and the origin of life
2 The biotic world
3 The theory of life's origins
4 Life at the very beginning I: the chemistry of the first biomolecules
5 Life at the very beginning II: the emergence of complex RNA molecules
6 The origin of life was an evolutionary transition in individuality
7 A synthesis for the origin of life

Part Two: The origin of death

8 Philosophical considerations and the origin of death
9 Observations of death
10 Mechanisms and measures of programmed cell death in the unicellular world
11 True PCD: when PCD is an adaptation
12 Ersatz PCD: the non-adaptive explanations for PCD
13 Programmed cell death and the levels of selection
14 A synthesis for the origin of programmed cell death

Part Three: Origins of life and death, and their coevolution

15 Group selection and the origins of life and death
16 Life and death coevolution, and the emergence of complexity
  Postface
Additional notes
Reference list
Index

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