基本説明
Demonstrates that autism, like mental retardation, is a clinical presentation of numerous different diseases, many with genomic underpinnings. In this ground-breaking work, the authors explain in great detail how to clinically diagnose infants, children, adolescents and adults with autistic behavioral features and their psychiatric and neurological work-ups. Fully details the many advances that have occurred in the field within the past 10 years since the last edition was published. Combines the separate research done by autism specialists and neuroscientists and blends these two sources, sorting out the relevant findings and characterizing the many remaining unsolved questions.
Full Description
The Autisms, written by Mary Coleman and Christopher Gillberg, demonstrates that autism, like mental retardation, is a clinical presentation of numerous different diseases, many with genomic underpinnings. In this ground-breaking work, the authors explain in great detail how to clinically diagnose infants, children, adolescents and adults with autistic behavioral features and their psychiatric and neurological work-ups.
This new edition contains several chapters on the associated problems of autism, such as intellectual disability, epilepsy, tics, eating disorders and sleep problems, as well as a chapter on epidemiology that documents the historical increase in autism diagnoses. Several chapters summarize the latest data on neuroanatomy, biochemistry and neuropsychology, while three neurogenomics chapters show evidence suggesting that autism occurs due to genetic errors which cause interruption or misdirection of critical neurodevelopmental circuits in the fetal brain.
Completely up-to-date, The Autisms is relevant and necessary reading for researchers and clinicians in neuroscience, neurology, pediatrics, psychiatry, and psychology.
Contents
Part One - The Autisms as a Spectrum ; 1. Diagnosis of the autisms in infancy ; 2. The clinical course of autism in childhood and adolescence ; 3. Adults with autism ; 4. Asperger syndrome ; 5. Comorbidities and symptom complexes ; 6. Epidemiology: is autism increasing? ; 7. Timing: When do diseases with autistic features begin? ; 8. Neuroanatomy: which parts of the brain are involved? ; 9. Neuropsychology and cognitive psychology in the autisms ; 10. Autism and epilepsy ; 11. Biochemistry, immunology, endocrinology ; Part Two - The Autisms as a Syndrome ; 12. Clinical subgroups ; 13. Neurogenomics: Genes ; 14. Neurogenomics: Chromosomes ; 15. Neurogenomics: Mitochondrial disorders, environment, epigenetics ; Part Three - Treatment and Support in the Autisms ; 16. Educational and behavioral interventions throughout the life span in autism ; 17. Prevention, reversal autism, and medical therapies ; 18. Conclusion ; Appendix One - Recommended psychiatric/psychological workup in autism. ; Appendix Two - Updated neurological workup for children with autistic features ; Glossary ; Index
