Metalloenzymes : From Bench to Bedside

Supuran, Claudiu T. (EDT)/ Donald, William Alexander (EDT)

Academic Press Inc（2023/09発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 634 p.
• 言語 ENG
• 商品コード 9780128239742
• DDC分類 572.752

Full Description

Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of magnesium, calcium, zinc, manganese, nickel, iron, copper, cadmium, molybdenum, and tungsten enzymes, along with catalytic roles within their active sites. With a uniform approach throughout, each chapter includes the structure and function of the enzyme, physiologic and pathologic roles, inhibitors and activators of the enzyme (and their design), and clinical agents or compounds applied in medicine and drug discovery. This book enables scientists across academia and industry to adopt ongoing metalloenzyme research, and continuous discovery of novel metalloenzymes, in new life science studies and clinical applications.

Contents

1. Introduction to metalloenzymes

Section II
2. Magnesium and calcium-containing enzymes

Section III
3. Zinc enzymes

Section IV. Other metalloenzymes
4. Manganese enzymes
5. Nickel enzymes
6. Iron enzymes (heme-containing)
7. Iron enzymes (non-heme containing, Fe(II) or Fe(III) proteins)
8. Copper enzymes
9. Cadmium enzymes
10. Molybdenum enzymes
11. Tungsten-containing enzymes