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Full Description
Aging: From Fundamental Biology to Societal Impact examines the interconnection of the cellular and molecular basis of aging and societal-based challenges and innovative interventions. Sections take a societal-based angle on aging, describing several flagship initiatives for healthy living and active aging in different regions, cover the biology of aging which includes the hallmarks of aging, explain the pathophysiology of aging, describing different comorbidities associated with aging and possible interventions to decrease the impact of aging, and envision future and innovative measures to tackle aging-related morbidities.
Contributions from an interdisciplinary panel of experts cover such topics as the biology of aging to physical activity, nutrition, psychology, pharmacology, health care, social care and urban planning.
Contents
Section 1. The Societal Burden of Aging
1. Aging at a global level
2. The financial and economical burden of aging worldwide
3. Flagship initiatives for healthy living and active aging in Europe
4. Flagship initiatives for healthy living and active aging in Africa
5. Flagship initiatives for healthy living and active aging in North America
6. Flagship initiatives for healthy living and active aging in Asia and Oceania
7. Flagship initiatives for healthy living and active aging in Central and South America
Section 2. The Biology of Aging
8. A metabolic and mitochondrial angle on aging
9. Intracellular communication and aging
10. Genomic instability and telomere attrition
11. Cellular senescence during aging
12. The epigenetics of aging
13. Disrupted cellular quality control mechanisms in aging
14. Deregulated nutrient sensing in aging
15. Stem cells fitness and aging
16. Programming of early aging
Section 3. Aging-related physiology, disease and prevention of aging-related diseases
17. Adherence to therapy and polymedication
18. Frailty and cognitive decline
19. Cardiovascular aging
20. Aging-related neoplasia
21. Inflammation
22. Geroscience: An unifying view on aging as a risk factor
23. Building healthy aging
Section 4: The Future and Innovation in Aging
24. The future of innovation in aging
25. Machine learning in the context of better healthcare in aging
26. The knowledge and research in aging for the future
27. The future of integrated care in aged individuals
28. Moving from reactive to preventive medicine
29. Personalized medicine: will this work for decreasing aging-related morbidities
30. Anti-aging interventions: myths and realities
