Full Description
Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase inhibitors (DNMTi), Histone deacetylases inhibitors (HDACi), Histone lysine demethylases inhibitors (HDMi), Histone lysine methyltransferases inhibitors (HMTi) and drugs regulating the microRNA, long non-coding RNA (lncRNA) or RNA methylation. Finally, recent and future developments of the field of epigenetic regulation are explored.
This is a valuable resource for cancer researchers, clinicians, graduate students and several members of biomedical field who are interested in learning about epigenetic regulation methods to reverse chemo-resistance in cancers.
Contents
1. The role of epigenetic regulation in cancer2. DNA methyltransferase inhibitors (DNMTi) as sensitizing agents to overcome chemoresistance3. Histone deacetylases inhibitors (HDACi) as sensitizing agents to overcome chemoresistance4. Histone lysine demethylases inhibitors (HDMi) as sensitizing agents to overcome chemoresistance5. Histone lysine methyltransferases inhibitors (HMTi) as sensitizing agents to overcome chemoresistance6. Drugs regulating the microRNA to overcome chemoresistance7. Drugs regulating the lncRNA to overcome chemoresistance8. Drugs regulating the mRNA methylation to overcome chemoresistance9. Future combined epigenetic therapy
