Full Description
OrthoBiologics provides state-of-the-art knowledge of current biologic therapies for a variety of orthopaedic conditions in a single source. The content is presented in a straightforward manner, including defining all currently available orthobiologic options, discussing processing characteristics and appropriate clinical use, and finally, summarizing clinical applications and outcomes as well as future potential directions.
In addition to covering current approaches and applications, the editors aim for this book to present "best practices" for those practicing and researching orthopaedic pathologies and orthobiologic treatments, including blood and cellular based therapies. The editors are world-renown experts in the field and this book fills a gap in the market.
Contents
1. Autologous blood; platelet-rich plasma and platelet-poor plasma
2. Defining, measuring and optimizing platelet-rich plasma
3. Optimal use of platelet-rich plasma and plateletpoor plasma
4. Where orthobiologics started: what are mesenchymal stem cells?
5. Bone marrow-derived mesenchymal stromal cells
6. Defining, optimizing, and measuring bone marrow aspirate and bone marrow concentrate
7. Optimal clinical use of bone marrow aspirate and bone marrow aspirate concentrate
8. Adipose mesenchymal stromal cells
9. Defining, optimizing, measuring, and utilizing adipose, MFAT, etc.
10. Optimal clinical use of adipose mesenchymalstromal cells
11. Basic science and preclinical evidence for amniotic membrane2derived allografts in
12. Defining, optimizing, and measuring amniotic/ placental mesenchymal stem cells
13. Optimal clinical use of amniotic/placental mesenchymal stem cells
14. Synovial mesenchymal stem cells
15. Peripheral blood stem cells
16. Orthobiologics—growth factors and mediators
17. Orthobiologics in the procedure room—who, what, where, when, and how
18. Orthobiologics in the operating room—who, what, where, when, and how
19. The changing regulatory environment: regulations and restrictions
20. Bioscaffolds for osteochondral injuries of the knee
21. Orthobiologics on the horizon
22. Complications associated with orthobiologics