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Full Description
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.
Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years.
Cell Sources for iPSCs, Volume 7 teaches readers about current advances in the field. It shares up-to-date comprehensive overviews of current advances in the field. This book describes the derivation of iPSCs from different sources in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development, and progression. The authors focus on the modern state-of-art methodologies and the leading-edge concepts in the field of stem cell biology. In recent years, remarkable progress has been made in the obtention of iPSCs and their differentiation into several cell types, tissues, and organs using state-of-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. Thus, this book is an attempt to describe the most recent developments in iPSCs biology, which is one of the rising hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of detailed chapters on how we derive iPSCs from distinct sources. Ten chapters written by experts in the field summarize the present knowledge about different cell sources for iPSCs.
This volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field.
Contents
1. Induced Pluripotent Stem Cells Derived from Amniotic Fluid Stem Cells
2. Induced Pluripotent Stem Cells from Spermatogonial Stem Cells: Potential Applications
3. Induced Pluripotent Stem Cell Derivation from Myoblasts
4. Lymphoblastoid-Derived Human-induced Pluripotent Stem Cells: A New Tool to Model Human Diseases
5. Oral Tissues as Sources for Pluripotent Stem Cell Derivation and their Applications for Neural, Craniofacial, and Dental Tissue Regeneration
6. Induced Pluripotent Stem Cell Derived from Ovarian Tissue
7. Muse Cells as a Robust Source of Induced Pluripotent Stem Cells
8. Prostate Cancer Reprogramming and Dedifferentiation into Induced Pluripotent Stem Cells
9. Melanoma-Derived Induced Pluripotent Stem Cells: A Model for Understanding Melanoma Cell of Origin and Drug Resistance
10. Induced Pluripotent Stem Cell Derived from Postmortem Tissue in Neurodegenerative Disease Research
