Oral Delivery of Therapeutic Peptides and Proteins

Tyagi, Puneet (EDT)/ Subramony, Anand (EDT)

Academic Press Inc（2022/08発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 316 p.
• 言語 ENG
• 商品コード 9780128210611
• DDC分類 615.6

Full Description

Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport.

Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource.

Contents

1. Formulation technologies being adopted for oral delivery of proteins and peptides
2. Modification of actives to make them more suited for oral delivery
3. Animal models and their shortcomings in assessing oral bioavailability
4. In vitro models to simulate drug absorption and transport
5. Futuristic technologies to improve oral bioavailability