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Full Description
Principles and Technologies for Electromagnetic Energy Based Therapies covers the theoretical foundations of electromagnetic-energy based therapies, principles for design of practical devices and systems, techniques for in vitro and in vivo testing of devices, and clinical application examples of contemporary therapies employing non-ionizing electromagnetic energy. The book provides in-depth coverage of: pulsed electric fields, radiofrequency heating systems, tumor treating fields, and microwave heating technology. Devices and systems for electrical stimulation of neural and cardiac issue are covered as well. Lastly, the book describes and discusses issues that are relevant to engineers who develop and translate these technologies to clinical applications.
Readers can access information on incorporation of preclinical testing, clinical studies and IP protection in this book, along with in-depth technical background for engineers on electromagnetic phenomena within the human body and selected therapies. It covers both engineering and biological/medical materials and gives a full perspective on electromagnetics therapies. Unique features include content on tumor treating fields and the development and translation of biomedical devices.
Contents
Section 1: Introduction and Theoretical Foundations
1. History, development and application of electromagnetic fields in medicine
2. Biophysical principles of electromagnetic field interactions with biological tissues
3. Computational methods for the modeling of electromagnetic fields in biological
tissues
3a. Low frequency, electrical spectrum (pulsed electric fields, TTF, RF)
3b. High frequency, electromagnetic spectrum (MW)
4. Thermal effects of electromagnetic fields
5. Tissue property determinants of electromagnetic therapies
Section 2: Pulsed Electric Fields
6. Introduction to PEF therapy and its applications
7. Working principles of PEF therapy
8. Instrumentation for PEF therapy
9. In vitro and in vivo testing of PEF therapy
10. Clinical application of PEF: Oncology
11. Clinical application of PEF: Other
Section 3: Radiofrequency Energy
12. Introduction to RF energy and its applications
13. Working principles of RF therapy
14. Instrumentation for RF therapy
15. In vitro and in vivo testing of RF therapy
16. Clinical application of PEF: Oncology
17. Clinical application of PEF: Other
Section 3: Tumor Treating Fields
18. Introduction to TTF and its applications
19. Working principles of TTF therapy
20. Instrumentation for TTF therapy
21. In vitro and in vivo testing of TTF therapy
22. Clinical application of TTF: Oncology
Section 4: Microwave Energy
23. Introduction to MW energy and its applications
24. Working principles of MW therapy
25. Instrumentation for MW therapy
26. In vitro and in vivo testing of MW therapy
27. Clinical application of MW: Oncology
28. Clinical application of MW: Other
Section 5: Non-Ablative Applications
29. Brain stimulation
30. Peripheral nerve stimulation
31. Cardiac pacemaker and defibrillators
32. Pain control
33. Emerging topics
Section 6: Development and Translation
34. Regulatory and approvals
35. Preclinical testing
36. Clinical trials and design
37 IP protection
38. Case study 1
39. Case study 2
