Full Description
Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.
Contents
1. Discovery of insulin
2. Structure and properties of insulin
3. Biosynthesis of insulin
4. Biosynthesis, intracellular-trafficking, and exocytosis of insulin granules
5. Regulation of insulin secretion
6. Regulation of insulin secretion
7. Direct and indirect actions of insulin: role of insulin receptor, glucose transporters (GLUTs), and sodium-glucose linked transporters (SGLTs)
8. Metabolic and physiological effects of insulin
9. Etiopathogenesis of insulin resistance
10. Insulin resistance syndrome
